Genome Editing for Neurodegenerative Diseases

<p>Introduction<br>Burkhard Poeggeler <br>1. Therapeutic potential of genome editing tools in neurodegenerative diseases<br>Ankur Kumar, Nandigam Pardhipa, Sachin G. Swami, Vibha Dwivedi and Anand K. Singh<br>2. Genetic and molecular basis of neurodegenerative diseases<br>Sunanda Yogi, Anjali Sangeeth, Anuradha Venkatakrishnan Chimata, Radhika Padma and Amit Singh<br>3. Genome editing tools: principles, structures, and mechanisms<br>Rayees Ahmad Naik, Mehak Naseer Mir, Roshni Rajpoot, Sonalika Singh, Kusum Singh and Sandeep Kumar Singh<br>4. Advances in CRISPER/Cas system and genome editing technologies for the treatment of neurodegenerative diseases<br>Shailendra Kumar Mishra, Hung-Ming Chang, Ahmad A. Obaid and Sandeep Kumar Singh<br>5. Use of CRISPR system in genetic screening to detect neurodegenerative disease<br>Koyel Kar<br>6. Epigenetic manipulation and gene regulation using the CRISPR/Cas system for neurodegenerative diseases<br>Josephine Esposto<br>7. Transgene delivery system: viral, nonviral, and other methods for central nervous system<br>Bhupender Sahu, Bibhudendu Behera and Umesh Kumar<br>8. Gene therapies for neurodegenerative disease: current knowledge and challenges<br>Bhumi Arora, Sakshi Garg, Aditya Shrivastav, Mrinalini Sharma, Bhupender Sahu and Umesh Kumar<br>9. Gene therapy under clinical trials for neurodegenerative diseases<br>Bhupender Sahu, Lakshita Tyagi, Prshant Tyagi and Umesh Kumar<br>10. Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics<br>Burkhard Poeggeler</p>