PART I: Clinical Evaluation <br>1. General Aspects of the Patient’s Neurologic History <br>2. Neurologic Examination of the Older Child <br>3. Neurologic Examination of Young Children (Ages 1–5 Years) <br>4. Neurologic Examination of Infants (Ages 0–1 Year) <br>5. Motor Signs <br>6. Vision Loss <br>7. Hearing Impairment <br>8. Vertigo <br>9. Taste and Smell <br>10. Neuropsychological Assessment <br><br>PART II: Care of the Child With Neurologic Disorders <br>11. Counseling Children With Neurologic Disorders and Their Families <br>12. Pediatric Neurorehabilitation Medicine <br>13. Pediatric Palliative Care, Pain, and Symptom Management <br>14. Practical Bioethics in Child Neurology <br>15. Transitional Care for Children With Neurologic Disorders <br>16. Practice Guidelines in Pediatric Neurology <br>17. Measurement of Health Outcomes in Pediatric Neurologic Disorders <br>18. Computer Resources, Artificial Intelligence, and Telemedicine <br>19. Education and Training of Child Neurologists and Workforce Issues <br><br>PART III: Neurodiagnostic Testing <br>20. Cerebrospinal Fluid Examination <br>21. Pediatric Neuroimaging <br>22. Pediatric Neurophysiologic Evaluation <br><br>PART IV: Global Child Neurology <br>23. Regional and Global Implications for Children’s Brain Health <br>24. Implementing Child Neurology Care in Resource-Limited Settings <br>25. Adaptation and Implementation of Guidelines at the Local Level <br><br>PART V: Neonatal Neurology <br>26. Neonatal Neuro-Intensive Care <br>27. Provoked Neonatal Seizures and Neonatal Onset Epilepsy <br>28. Hypoxic-Ischemic Brain Injury in the Term Newborn <br>29. Cerebrovascular Disorders in the Newborn <br>30. Neonatal Nervous System Trauma <br>31. Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury <br>32. Perinatal Metabolic Encephalopathies <br><br>PART VI: Environment and Brain Development <br>33. The Neural Exposome and Environmental Neuroscience <br>34. Adverse Childhood Experiences <br>35. The Neurological Impact of Prenatal Substance Exposure <br>36. Environmental Pollutants <br>37. Malnutrition, Nutrition, and Dietary Toxins <br>38. Poisoning and Drug-Induced Neurologic Diseases <br><br>PART VII: Congenital Structural Defects <br>39. Introduction to Human Brain Malformations <br>40. Disorders of Neural Tube Development <br>41. Disorders of Forebrain Development <br>42. Disorders of Cerebellar and Brainstem Development <br>43. Microcephaly and Megalencephaly: Disorders of Brain Size <br>44. Malformations of Cortical Development <br>45. Hydrocephalus, Cysts, and Cystic Malformations <br>46. Congenital Anomalies of the Skull <br>47. Prenatal Diagnosis of Structural Brain Anomalies <br><br>PART VIII: Neurogenetics <br>48. Neurogenetics in the Genome Era <br>49. Genetic Counseling in the Genomic Era <br>50. Chromosomes and Chromosomal Abnormalities <br>51. Single-Gene Abnormalities <br>52. Neurocutaneous Disorders <br>53. Emerging Gene-Based Pathways: Channelopathies (Epilepsy and Beyond) <br>54. Emerging Gene-Based Pathways: mTORopathies <br>55. Emerging Gene-Based Pathways: RASopathies <br>56. Emerging Gene-Based Pathways: Chromatin Remodeling Disorders <br>57. The Neuronal Ceroid Lipofuscinoses <br><br>PART IX: Metabolic Disorders <br>58. Approach to the Patient With a Metabolic Disorder <br>59. Aminoacidemias and Organic Acidemias <br>60. Urea Cycle Disorders <br>61. Diseases Associated With Primary Abnormalities in Carbohydrate Metabolism <br>62. Disorders of Glycosylation <br>63. Lysosomal Storage Diseases <br>64. Mitochondrial Diseases <br>65. Peroxisomal Disorders <br>66. Neurotransmitter-Related Disorders <br>67. Disorders of Vitamin Metabolism <br><br>PART X: Neurodevelopmental Disorders <br>68. Neurodevelopmental Disabilities: Conceptual Framework <br>69. Intellectual Developmental Disorder and Global Developmental Delay <br>70. Regressive and Degenerative Genetic Neurological Disorders <br>71. Developmental Encephalopathies <br>72. Developmental Language Disorders <br>73. Nonverbal Learning Disorders <br>74. Dyslexia <br>75. Attention-Deficit/Hyperactivity Disorder <br>76. Autism Spectrum Disorder <br>77. Cerebral Palsy <br>78. Developmental Coordination Disorder <br>79. Treatment of Neurodevelopmental Disorders <br>80. Neuropsychopharmacology <br><br>PART XI: Epilepsy <br>81. Overview of Seizures and Epilepsy in Children <br>82. Principles of Management and Outcome <br>83. Pathophysiology of Seizures and Epilepsy <br>84. Epilepsy Genetics <br>85. Febrile Seizures <br>86. Generalized Seizures <br>87. Focal and Multifocal Seizures <br>88. Myoclonic Seizures <br>89. Infantile Epileptic Spasms Syndrome <br>90. Status Epilepticus <br>91. Electroclinical Syndromes: Neonatal Onset <br>92. Electroclinical Syndromes: Infantile Onset <br>93. Electroclinical Syndromes: Childhood Onset <br>94. Electroclinical Syndromes: Adolescent Onset <br>95. Focal Structural Epilepsy <br>96. Acquired Epilepsies: Trauma, Stroke, and Tumors <br>97. Inherited Metabolic Epilepsies <br>98. Antiseizure Medication Therapy in Children <br>99. Epilepsy Surgery in the Pediatric Population <br>100. Neuromodulation in Epilepsy <br>101. Ketogenic Diets <br>102. Behavioral, Cognitive, and Social Implications of Childhood Epilepsy <br>103. Mortality in Children With Epilepsy <br><br>PART XII: Nonepileptiform Paroxysmal Disorders <br>104. Headache in Children and Adolescents <br>105. Breath-Holding Spells and Reflex Anoxic Seizures <br>106. Psychogenic Nonepileptic Seizures and Psychiatric Disorders <br>107. Functional Neurological Symptom Disorder in Children and Adolescents <br>108. Syncope and Postural Orthostatic Tachycardia Syndrome <br>109. Brief Resolved Unexplained Events, Apparent Life-Threatening Events, and Sudden Infant Death Syndrome <br><br>PART XIII: Disorders of Sleep <br>110. Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents <br>111. Nocturnal Paroxysmal Disorders <br>112. Disorders of Excessive Sleepiness <br><br>PART XIV: Disorders of Balance and Movement <br>113. The Cerebellum and the Hereditary Ataxias <br>114. Movement Disorders: An Overview <br>115. Paroxysmal Dyskinesias <br>116. Movement Disorders of Infancy <br>117. Drug-Induced Movement Disorders in Children <br>118. Tics and Tourette Syndrome <br><br>PART XV: White Matter Disorders <br>119. Genetic and Metabolic Disorders of the White Matter <br>120. Acquired Disorders Affecting the White Matter <br><br>PART XVI: Brain Injury and Disorders of Consciousness <br>121. Impairment of Consciousness and Coma <br>122. Traumatic Brain Injury in Children <br>123. Abusive Head Trauma <br>124. Hypoxic-Ischemic Encephalopathy in Infants and Older Children <br>125. Disorders of Intracranial Pressure <br>126. Spinal Cord Injury <br>127. Determination of Brain Death/Death by Neurologic Criteria in Infants and Children <br><br>PART XVII: Cerebrovascular Disease in Children <br>128. Arterial Ischemic Stroke in Infants and Children <br>129. Sinovenous Thrombosis <br>130. Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children <br>131. Cerebral Arteriopathies <br>132. Coagulation Disorders and Cerebrovascular Disease in Children <br><br>PART XVIII: Infections of the Nervous System <br>133. Bacterial Infections of the Nervous System <br>134. Viral Infections of the Nervous System <br>135. Fungal, Rickettsial, and Parasitic Diseases of the Nervous System <br>136. Neurologic Complications of Immunization <br><br>PART XIX: Immune-Mediated Disorders of the Nervous System <br>137. Diagnosis and Management of Pediatric Neuroimmunological Disorders <br>138. Autoimmune Encephalitis <br>139. Autoimmune-Associated Epilepsies <br>140. Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus, and Pediatric Acute Neuropsychiatric Syndrome <br>141. Immune-Mediated Cerebellar Disorders <br>142. Neurorheumatology <br><br>PART XX: Pediatric Neuro-Oncology <br>143. Pediatric Neuro-Oncology: An Overview <br>144. Medulloblastoma <br>145. Other Embryonal and Pineal Malignancies of the Central Nervous System <br>146. Ependymoma <br>147. Pediatric-Type Diffuse High-Grade Glioma <br>148. Pediatric Low-Grade Glioma <br>149. Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma <br>150. Atypical Teratoid/Rhabdoid Tumors <br>151. Central Nervous System Germ Cell Tumors<br>152. Craniopharyngiomas, Meningiomas, and Schwannomas<br>153. Pediatric Intradural Spinal Cord Tumors<br>154. Systemic Cancers and Central Nervous System Involvement<br>155. Treatment-Related Neurologic Sequelae of Pediatric Central Nervous System Tumors<br><br>PART XXI: Neuromuscular Disorders<br>156. Muscle and Nerve Development in Health and Disease<br>157. Diagnostic Testing in Children With Suspected Neuromuscular Disorders<br>158. Clinical Assessment of Pediatric Neuromuscular Disorders<br>159. The Floppy Infant<br>160. Classic Proximal Spinal Muscular Atrophy<br>161. Other Motor Neuron Diseases of Childhood<br>162. Genetic Peripheral Neuropathies<br>163. Acquired Peripheral Neuropathies<br>164. Inflammatory Neuropathies<br>165. Congenital Myasthenic Syndromes<br>166. Acquired Disorders of the Neuromuscular Junction<br>167. Duchenne and Becker Muscular Dystrophy<br>168. Congenital, Limb-Girdle, and Other Muscular Dystrophies<br>169. Congenital Myopathies<br>170. Metabolic Myopathies<br>171. Inflammatory Myopathies<br>172. Channelopathies: Myotonic Disorders and Periodic Paralysis<br>173. Multidisciplinary Management of Children With Neuromuscular Conditions<br><br>PART XXII: Systemic and Autonomic Nervous System Diseases<br>174. Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence<br>175. Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice<br>176. Disorders of Micturition and Defecation<br>177. Neurologic Disorders in Children With Heart Disease<br>178. Neurologic Disorders Associated With Renal Diseases<br>179. Neurologic Manifestations and Disorders Associated With Gastrointestinal Diseases<br><br>Index