Rajesh Krishna,
Lawrence Yu
Springer US
2008e druk, 2007
9780387723785
Biopharmaceutics Applications in Drug Development
Specificaties
Gebonden, 396 blz.
|
Engels
Springer US |
2008e druk, 2007
ISBN13: 9780387723785
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.
Specificaties
ISBN13:9780387723785
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:396
Uitgever:Springer US
Druk:2008
Inhoudsopgave
to Biopharmaceutics and its Role in Drug Development.- Molecular and Physicochemical Properties Impacting OralAbsorptionofDrugs.- Dissolution Testing.- Drug Absorption Principles.- Evaluation of Permeability and P-glycoprotein Interactions: Industry Outlook.- Excipients as Absorption Enhancers.- IntestinalTransporters in Drug Absorption.- Bioavailability and Bioequivalence.- A Biopharmaceutical Classification System Approach to Dissolution: Mechanisms and Strategies.- Food Effects on Drug Bioavailability: Implications for New and Generic Drug Development.- In Vitro–In Vivo Correlation on Parenteral Dosage Forms.- In Vitro–In Vivo Correlation in Dosage Form Development: Case Studies.