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Phylogenomics

Foundations, Methods, and Pathogen Analysis

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2024
ISBN13: 9780323998864
Rubricering
Elsevier Science e druk, 2024 9780323998864
€ 187,00
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Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

Specificaties

ISBN13:9780323998864
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>PART I. GENERAL TOPICS AND FOUNDATIONS<br>1. Phylogenomic analysis and the origin and early evolution of viruses<br>2. Application of Next Generation Sequencing for Genetic and Phenotypic Studies of Bacteria <br>3. Genomic insight into deciphering bacterial outbreaks <br>4. Drug resistance in bacteria, molecular mechanisms and evolution <br>5. Virulence evolution of bacterial species <br>PART II. METHODS IN THE PHYLOGENOMICS <br>6. Modeling evolutionary changes of k-mer patterns of bacterial genomes <br>7. Clock Rates and Bayesian Evaluation of Temporal Signal <br>8. Microbial evolutionary reconstruction in the presence of mosaic sequences<br>9. Tools for SNP calling and the way to deal with big datasets<br>PART III. PHYLOGENOMICS OF SPECIFIC PATHOGENS <br>10. Phylogenomics of Yersinia pestis <br>11. Salmonella Phylogenomics<br>12. The phylogenomics of Shigella spp. <br>13. Phylogenomic diversity within Corynebacterium diphtheriae, a re-emerging threat to global public health<br>14. Phylogenomics of the East Asian lineage of Mycobacterium tuberculosis<br>15. Mycobacterium kansasii<br>16. Taxonomy and phylogenomics of Leptospira <br>17. Phylogenomics and evolution of Measles virus<br>18. Phylogenomics of HIV-1<br>19. Respiratory syncytial virus<br>20. Phylogenomics of Flaviviruses <br>21. How clonal is Staphylococcus aureus? <br>22. Genomic research of ancient pathogens in Central Asia<br>23. Subspecific nomenclature of the Cryptococcus neoformans/gattii complex and the predominant clonal evolution (PCE) model <br>24. Phylogenomics of Mycobacterium leprae <br><br> </p>
€ 187,00
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        Phylogenomics