Pharmacokinetics and Toxicokinetic Considerations - Vol II

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2022
ISBN13: 9780323983679
Rubricering
Elsevier Science e druk, 2022 9780323983679
Verwachte levertijd ongeveer 8 werkdagen

Samenvatting

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices.

Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.

Specificaties

ISBN13:9780323983679
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

1. Basic principles and concept in Toxicokinetic<br>2. Factors Influencing Drug Toxicity<br>3. Molecular biology of apoptotic, necrotic and necroptotic cell death<br>4. Toxicogenomic in drug safety assessment<br>5. Understanding the concept of signal toxicity<br>6. Importance of toxicity testing<br>7. Methods and Models for in vitro toxicity<br>8. New Emerging technologies for genetic toxicity testing<br>9. Zebrafish models for toxicological screening<br>10. Impact of ageing on the pharmacokinetics and pharmacodynamics of the drugs<br>11. Food-Drug Interactions and their Implications on Oral Drug Bioavailability<br>12. Drug-Drug interactions and their implications on the Pharmacokinetics of the Drugs<br>13. Clinical Importance of Herb-Drug interaction<br>14. Insilico methods for the prediction of drug toxicity<br>15. Organ-on-a-chip for assessing environmental toxicants<br>16. Toxicity and toxicokinetics consideration in product development and drug research<br>17. Drug Toxicity and Forensic Pharmacokinetics <br>18. Excipient’s toxicity and safety<br>19. Pharmaceutical excipients: Special focus on Adverse drug interactions<br>20. Emerging role of novel excipients in drug product development and their safety concerns<br>21. Toxicity of Pharmaceutical azo dyes<br>22. Environmental and Safety Aspects of Bionanotechnology<br>23. Toxicological Risk assessment of medical devices<br>24. Developmental toxicity of nanomaterials used in healthcare<br>25. Ethical defilements in clinical research and potential roles of Institutional review board<br>26. Toxicodynamic in Drug research

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        Pharmacokinetics and Toxicokinetic Considerations - Vol II