<p>Immunologic Sciences <br>-Mucosal immunity<br>-Tolerance<br>-Immunology of IgE mediated allergy<br>-Immunology of non-IgE mediated allergy<br>-B cell compartment<br>-T cell compartment<br>-Effector cells<br>-Antigen presenting cells<br>-Route of senstization<br>-Mouse models<br>-In vitro studies<br>-Genetics of FA<br>-Microbiome<br>-Systems biology to understand food allergy<br><br>Food sciences applicable to allergy (allergens, additives, toxins, measurement/detection)<br>-Molecular characteristics of food allergens<br>-Nomenclature food allergens<br>-Review of allergens<br>Egg<br>Milk<br>Grains<br>Soy and legumes<br>Peanut<br>Tree nuts<br>Fish<br>Shellfish<br>Sesame and seeds<br>Fruit allergy<br>Vegetable allergy<br>Cross reactivity<br>Meat allergies (note alpha gal is covered under disease states)<br>Allergy to protein additives/colors (carmine, pectin, gelatin, etc)<br>-Genetic engineering<br>-Thresholds<br>-Labeling food allergens-studies<br>-Labelling food allergens-laws<br>-Allergen detection systems<br>-Food additives and preservatives (multiple chapters with allergic implication<br>-Sulfites<br>-MSG<br>-Tartrazine, azo/non-azo dyes,<br>-Antioxidants,<br>-Benzoates, parabens,<br>-Colorings, flavorings,<br>-Natural protein-based additives<br>-Food toxins<br>-Pharmacologic reactions to foods</p><p>Definitions, epidemiology, economics, quality of life, psychosocial impact<br>Food allergy definitions and overview (IgE, non-IgE, mixed]<br>Food intolerance (break down types)<br>Common food allergens and food groups/clinical implications and cross-reactivity<br>Food allergy pediatric versus adult epidemiology<br>Natural course of food allergy<br>Tools for epidemiologic determination of food allergy<br>Epidemiology of food allergy, prevalence<br>Food allergy risk factors<br>Economics<br>Disparities<br>Quality of life (QOL)<br>QOL instruments<br>Anxiety<br>Bullying (not management)</p><p>Disease states of IgE mediated allergy <br>Atopic Dermatitis [diagnosis, management, role of food]<br>Pollen-food related syndrome [overview, relationships, management]<br>Urticaria/angioedema<br>Respiratory tract<br>Oral allergy syndrome/pollen-food allergy syndrome<br>Food Induced Anaphylaxis<br>Food associated exercise-induced anaphylaxis<br>Alpha-gal allergy</p><p>Disease states of non-IgE mediated/mixed pathophysiology gastrointestinal allergy *each state likely needs sub-topics [15-20 chapters]<br>Food protein induced enterocolitis syndrome [definitions, diagnosis, management, natural course]<br>Food protein induced proctocolitis<br>Eosinophilic esophagitis<br>Eosinophilic gastritis<br>Eosinophilic colitis<br>Eosinophilic gastroenteritis<br><br>Intolerance and other adverse reactions to foods <br>Overview<br>Lactose intolerance<br>Hereditary/metabolic disorders<br>Alcohol dehydrogenase deficiency<br>Celiac disease<br>Role of food: colic, constipation<br>Role of food: IBS, IBD<br>Mast cell disorders and food allergy<br>Autism/developmental disorders and foods<br>Headaches and neurological issues and foods<br>Rheumatologic diagnoses and foods<br>Skin responses not related to atopic dermatitis or urticarial (FFE, physical urticarial)<br>Primary immunodeficiency with implications for food allergy<br>Asthma and food additives</p><p>Diagnostics <br>General approach (history, physical, prior probability assessment, test selection)<br>Natural course related to diagnostics<br>Skin tests<br>Serum IgE with whole proteins<br>Component tests<br>Diagnostics with regard to cross-reactivity<br>Epitope testing<br>BAT<br>MAT<br>Elimination diets<br>Oral food challenges (multiple)<br>Incorporating history and testing<br>Novel testing/monitoring<br>Unproven methods<br><br>Management [15-20 chapters]<br>Nutrition topics (multiple and by ages), including daily management<br>Occupational food allergy<br>QOL/anxiety/bullying<br>Age differences in management [infant/child/teen-young adult/adult]<br>Restaurants<br>School<br>Anaphylaxis plans<br>Label reading<br>Home management<br>Vaccine and medication allergies related to food allergies<br>Lay organizations and general resources for food allergy<br><br>Prevention <br>Overview of current recommendations (global)<br>Role of maternal diet<br>Role of breastfeeding<br>Role of infant formula<br>Early diet<br>Microbiome/prebiotics/probiotics/synbiotics<br>Skin barrier<br>Diet diversity<br>Nutrients, vitamin D<br>Novel methods for primary and secondary prevention</p><p>Therapeutic approaches <br>Overview<br>Oral immunotherapy [overview/approach/safety-efficacy others]<br>Sublingual immunotherapy<br>Immunotherapies with modified proteins or DNA vaccines<br>Adjuvants<br>Biologics-proteins<br>Small molecule therapeutics<br>Shared decision making for therapeutics<br>Quality of life and therapeutics</p>
