1. The Structure and Regulation of the Immunoglobulin Loci<br>Joseph S. Lucas, Cornelis Murre, Ann J. Feeney and Roy Riblet<br>2. The Mechanism, Regulation and Evolution of V(D)J Recombination<br>David G. Schatz, Yiwen Zhang, Jianxiong Xiao, Shan Zha, Yu Zhang and Frederick W. Alt<br>3. The Origin of V(D)J Diversification<br>Ellen Hsu and Susanna M. Lewis<br>4. The Variable Lymphocyte Receptor B System of the Jawless Vertebrates<br>Thomas Boehm, Max D. Cooper, Masayuki Hirano, Sabyasachi Das, Ryo Morimoto and Jonathan P. Rast<br>5. Structure and Signalling Function of the B-Cell Antigen Receptor and Its Coreceptors<br>Michael Reth, Kathrin Klasener, Lars Nitschke and Michael R. Gold<br>6. Fc Receptors<br>Jeffrey V. Ravetch and Stylianos Bournazos<br>7. Transcriptional Regulation of Early B-Cell Development<br>Ashley P. Ng, Rhiannon Morris and Stephen L. Nutt<br>8. Relationship between B-Cell Populations, Development and Function of B-Cell Subsets<br>Eva Piano Mortari and Rita Carsetti<br>9. B-Cell Development to Immunity and Tolerance<br>Fritz Melchers, Mir-Farzin Mashreghi and Peter K. Jani<br>10. The Role of the BAFF and Lymphotoxin Pathways in B Cell Biology<br>Fabienne Mackay and Jennifer L. Gommerman<br>11. Mechanism and Regulation of Immunoglobulin Class Switch Recombination<br>Fei-Long Meng, Lekha Nair, Keith C. Fernandez, Uttiya Basu and Jayanta Chaudhuri<br>12. Somatic Hypermutation<br>Jana Ridani, Philip Barbulescu, Alberto Martin and Javier M. Di Noia<br>13. Molecular Mechanism of Activation-Induced Cytidine Deaminase<br>Nasim A. Begum, Maki Kobayashi, Hitoshi Nagaoka and Tasuku Honjo<br>14. Molecular Pathogenesis of B-Cell Lymphomas<br>Laura Pasqualucci, Pantaleo De Simone and Riccardo Dalla-Favera<br>15. Human Immunodeficiencies Caused by Inborn Errors of B-Cell Development or Function<br>Stuart G. Tangye, Jean-Laurent Casanova and Cindy S. Ma<br>16. Memory B Cells and Plasma Cells<br>Mairi Anne McGrath, Florian Weisel, Andreas Radbruch and Mark Shlomchik<br>17. Homoeostatic Versus Pathogenic Autoantibodies: Origin, Structure and Effector Functions<br>Yemil Atisha-Fregoso, Rita Pozovskiy, Shabirul Haque, Manami Watanabe, Yong-Rui Zou and Betty Diamond<br>18. Anti-Tumour Necrosis Factor and New Paradigms for Therapies Using Antibodies<br>Sergei A. Nedospasov, Marina S. Drutskaya and Andrey A. Kruglov<br>19. Therapeutic Targeting of B Cells and Plasma Cells with a Focus on Multiple Sclerosis and Other Autoimmune Conditions<br>Andreia C. Lino and Thomas Dorner<br>20. IMGT Immunoglobulin Repertoire<br>Analysis and Antibody Humanization Marie-Paule Lefranc<br>21. Mucosal Immunity to Bacteria and Immunoglobulin A Synthesis<br>Andrew J. Macpherson, Tim Rollenkse, Lucia M. Kato and Sidonia Fagarasan<br>22. B-Cell Metabolism<br>Julia Jellusova
