Coronavirus Drug Discovery

<p>PART 1: DRUGGABLE TARGETS AND SIGNALING PATHWAYS <br>1. SARS-CoV-2 genome sequencing and promising druggable targets<br>2. Signaling pathways implicated in SARS-CoV2 infection<br>3. Roles of membrane lipids and lipid synthesis inhibitors in the propagation of coronavirus disease<br>4. Potential Drugs in SARS-CoV-2 Treatment: Key Features and Mechanisms of Actions</p> <p>PART 2: COMPUTATIONAL APPROACHES<br>5. Application of computational tools for coronavirus drug discovery<br>6. In silico Approaches in Drug Discovery for SARS-CoV-2<br>7. Application of molecular docking and dynamics tools in SARS-CoV-2 drug design: Ligand-protein interaction studies<br>8. Molecular dynamic simulation with protein and detection of repurposable drugs for COVID-19 <br>9. Computation-guided inhibitor screening against the nucelocapsid of SARS-CoV-2 <br>10. In-silico insight into the interaction of 4-aminoquinolines with selected SARS-CoV-2 structural and non-structural proteins <br>11. In silico Evaluation of Anti-SARS-CoV-2 Activity of Punica granatum L. Phytochemicals<br>12. In silico Investigation and Identification of Bioactive Compounds from Medicinal Plants as Potential Inhibitors against SARS-CoV-2 Cellular Entry </p>