Part I – Fundamentals of Inflammasome Biology <br>1. Overview of inflammatory processes at cellular level<br>2. Inflammasome formation and triggers<br>3. Cellular signaling, molecular activation and regulation of the NLRP1 inflammasome<br>4. Cellular signaling, molecular activation and regulation of the NLRP3 inflammasome<br>5. Cellular signaling, molecular activation and regulation of the NLRP6 inflammasome<br>6. Cellular signaling, molecular activation and regulation of the NLRC4 inflammasome<br>7. Cellular signaling, molecular activation and regulation of the AIM2 inflammasome<br>8. Cellular signaling, molecular activation and regulation of the Pyrin inflammasome<br>9. Cellular signaling, molecular activation and regulation of the non-canonical inflammasome<br>10. Cellular signaling, molecular activation and regulation of auto-active inflammasomes<br>11. Autophagy and the inflammasome<br>12. Inflammasome effector functions<br>13. Inflammatory caspases<br>14. Structural aspects of inflammasomes<br>15. Evolutive aspects of inflammasomes<br><br>Part II – inflammasome role in disease processes <br>16. The inflammasome in cardiovascular diseases <br>17. Inflammasome implications in metabolic disorders <br>18. Inflammasome in venous thromboembolic disorders <br>19. Inflammasomes and neurodegenerative diseases<br>20. Inflammasome implication in diseases of the respiratory system<br>21. Inflammasomes and their regulation in oral disease <br>22. Inflammasomes in inflammatory bowel disease pathogenesis <br>23. Inflammasome induced inflammation and fibrosis in liver<br>24. Inflammasomes in sepsis<br>25. The Inflammasome in viral, bacterial and fungal infections<br>26. Autoinflammatory syndromes<br>27. The inflammasome in graft-versus-host disease<br>28. Implication of the inflammasomes in rheumatic diseases<br>29. The inflammasomes in kidney disease<br>30. Inflammasomes and cancer<br>31. Inflammasomes in the pathobiology of degenerative retinopathies.<br><br>Part III – Inflammasome crosstalk in Cell Death <br>32. Regulation of pyroptosis by inflammasomes.<br>33. Crosstalk between necroptosis and inflammasome.<br>34. Apoptosis and inflammasome regulation<br>35. Implication of inflammasomes regulating different types of cell death<br>36. Regulation of neutrophil NETosis by inflammasomes<br><br>Part IV – Therapeutic Opportunities <br>37. Therapeutic opportunities targeting the inflammasome<br>38. Development of selective inflammasome Inhibitors<br>39. Natural compounds blocking inflammasomes<br>40. Inhibitors targeting inflammasome effectors<br>41. Multi-inflammasome inhibitors
