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Polymer-Drug Conjugates

Linker Chemistry, Protocols and Applications

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2023
ISBN13: 9780323916639
Rubricering
Elsevier Science e druk, 2023 9780323916639
€ 187,00
Levertijd ongeveer 8 werkdagen

Samenvatting

Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding.

The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

Specificaties

ISBN13:9780323916639
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. Drug Delivery: The conceptual perspectives and therapeutic applications <br>2. Rational design of linkers in polymer drug conjugates<br>3. Exploration of polymers in drug delivery: The structural and functional considerations<br>4. Chemistry of conjugation in drug delivery: The prospects of biodegradable and non-biodegradable bonds<br>5. Polymer-drug conjugation using ester and orthoester bond: Mechanism, protocols and applications<br>6. Polymer-drug linking through amide bonds: The chemistry and applications in drug delivery <br>7. Drug-Polymer conjugate tailoring by disulfide linkage and its exploration in drug distribution<br>8. Thioether linkage Chemistry: Perspectives and prospects in therapeutic designing<br>9. Drug targeting to cancer cells through stimuli responsive imine bonds: Fascinating aspects of site specificity <br>10. Carbamate-drug conjugates in drug delivery: Structural and mechanistic considerations<br>11. Bonding through phosphodiester moiety: Its implications in pharmaceutical modifications <br>12. Enzymatically degradable linkers<br>13. Dendrimer-Drug conjugates<br>14. Antibody-Drug conjugates<br>15. Polymer-Drug Conjugates in Clinical Trials: Challenges, Opportunities and Future prospects
€ 187,00
Levertijd ongeveer 8 werkdagen

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        Polymer-Drug Conjugates