Diagnostic Pathology: Genitourinary

Name: Diagnostic Pathology: Genitourinary
Author: Mahul B. Amin

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Gebonden, blz. | Engels

Elsevier Health Sciences | e druk, 2022

ISBN13: 9780323763325

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Elsevier Health Sciences e druk, 2022 9780323763325

Onderdeel van serie Diagnostic Pathology

€ 382,24

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**Selected for Doody’s Core Titles® 2024 in Urology**

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of genitourinary pathology, it incorporates the most recent clinical, pathologic, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Genitourinary is a one-stop reference for accurate, complete surgical pathology reporting, ideal as a day-to-day reference or as a reliable training resource.Covers nearly 200 diagnoses of the kidney, bladder, prostate, testis, paratestis, and penis, including details on the rapid changes and continuous advances in the diagnosis of genitourinary cancersIncludes the latest WHO (2022) and AFIP classifications/nomenclatures of tumors of the kidney, bladder, prostate, testis, and paratestis, as well as updated general conceptsFeatures thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of stains, and full-color illustrationsContains the latest staging information released in the most recent AJCC Cancer Staging Manual with a focus on practical issues pertaining to pathologic staging in resection specimensProvides expert guidance on differential diagnostic mimics in the text, as well as in the image galleries (unique to this book)Covers new and clinically relevant immunohistochemical (IHC) markersProvides relevant details and updates from the multiomic (or whole-genome) approach as relevant to pathology practiceDiscusses the latest changes in precision medicine and continuous advances in oncology research, including the discovery of new urologic cancer biomarkersFeatures a templated, highly formatted design and concise, bulleted text; diagnostic pearls, key facts in each chapter; and an extensive index for easy referenceIncludes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

Specificaties

ISBN13:9780323763325

Taal:Engels

Bindwijze:Gebonden

Uitgever:Elsevier Health Sciences

Serie:Diagnostic Pathology

Inhoudsopgave

SECTION 1: KIDNEY Introduction and Overview 1. Introduction to Renal Cell Tumors Satish K. Tickoo, MD and Victor E. Reuter, MD 10 Classification of Kidney Tumors and Tumor-Like Lesions Satish K. Tickoo, MD and Victor E. Reuter, MD Familial Cancer Syndromes 12 von Hippel-Lindau Syndrome Satish K. Tickoo, MD and Victor E. Reuter, MD 16 Birt-Hogg-Dubé Syndrome Satish K. Tickoo, MD and Victor E. Reuter, MD 20 Hereditary Leiomyomatosis Renal Cell Carcinoma Syndrome Satish K. Tickoo, MD, Victor E. Reuter, MD, and Mahul B. Amin, MD 24 Tuberous Sclerosis Complex Satish K. Tickoo, MD and Victor E. Reuter, MD 28 Succinate Dehydrogenase Complex Deficiency Syndrome Satish K. Tickoo, MD and Victor E. Reuter, MD 32 Hereditary Papillary Renal Cancer and Miscellaneous Other Familial Cancer Syndromes Satish K. Tickoo, MD and Victor E. Reuter, MD Nonneoplastic Lesions 38 Renal Tuberculosis, Xanthogranulomatous Pyelonephritis, Renal Malakoplakia Satish K. Tickoo, MD and Victor E. Reuter, MD Renal Cell Tumors, Benign 44 Papillary Adenoma Satish K. Tickoo, MD and Victor E. Reuter, MD 48 Renal Oncocytoma Satish K. Tickoo, MD and Victor E. Reuter, MD Renal Cell Carcinoma 54 Clear Cell Renal Cell Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 64 Multilocular Cystic Renal Neoplasm of Low Malignant Potential Satish K. Tickoo, MD and Victor E. Reuter, MD 68 Clear Cell Renal Cancers With Fibromyomatous Stroma, Including ELOC (Formerly TCEB1) Mutated Renal Cell Carcinoma Judy Sarungbam, MD, Satish K. Tickoo, MD, and Victor E. Reuter, MD 74 Clear Cell Papillary Renal Cell Tumor Satish K. Tickoo, MD and Victor E. Reuter, MD 82 Papillary Renal Cell Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 92 Chromophobe Renal Cell Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 100 Collecting Duct Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 106 SMARCB1-Deficient Renal Medullary Carcinoma and SMARCB1-Deficient Medullary-Like Renal Cell Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 112 TFE3- and TFEB-Rearranged Renal Cell Carcinomas Satish K. Tickoo, MD and Victor E. Reuter, MD 120 Mucinous Tubular and Spindle Cell Carcinoma Satish K. Tickoo, MD, Yingbei Chen, MD, and Victor E. Reuter, MD 126 Tubulocystic Renal Cell Carcinoma Satish K. Tickoo, MD, Judy Sarungbam, MD, and Victor E. Reuter, MD 130 Thyroid-Like Follicular Carcinoma of Kidney Satish K. Tickoo, MD and Victor E. Reuter, MD 134 Acquired Cystic Disease-Associated Renal Cell Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 140 Fumarate Hydratase-Deficient Renal Cell Carcinoma Jatin S. Gandhi, MD and Mahul B. Amin, MD 144 ALK Rearrangement-Associated Renal Cell Carcinoma Jatin S. Gandhi, MD and Mahul B. Amin, MD 148 Eosinophilic Solid and Cystic Renal Cell Carcinoma Jatin S. Gandhi, MD and Mahul B. Amin, MD 150 Other Eosinophilic/Oncocytic Tumors, Including ESC, EVT, and LOT Satish K. Tickoo, MD and Victor E. Reuter, MD 154 Subsequent 2nd Tumors Satish K. Tickoo, MD and Victor E. Reuter, MD 158 Renal Cell Carcinoma, Not Otherwise Specified Satish K. Tickoo, MD and Victor E. Reuter, MD Metanephric Tumors 162 Metanephric Adenoma Satish K. Tickoo, MD and Victor E. Reuter, MD 168 Metanephric Tumors Other Than Metanephric Adenoma Satish K. Tickoo, MD and Victor E. Reuter, MD Nephroblastic Tumors 172 Nephrogenic Rests Satish K. Tickoo, MD and Victor E. Reuter, MD 176 Nephroblastoma (Wilms Tumor) Satish K. Tickoo, MD and Victor E. Reuter, MD 186 Cystic Partially Differentiated Nephroblastoma Satish K. Tickoo, MD and Victor E. Reuter, MD Mesenchymal Tumors 188 Angiomyolipoma Satish K. Tickoo, MD and Victor E. Reuter, MD 194 Epithelioid Angiomyolipoma/Epithelioid PEComa Satish K. Tickoo, MD and Victor E. Reuter, MD 200 Congenital Mesoblastic Nephroma Satish K. Tickoo, MD and Victor E. Reuter, MD 204 Clear Cell Sarcoma of Kidney Satish K. Tickoo, MD and Victor E. Reuter, MD 208 Rhabdoid Tumor of Kidney Satish K. Tickoo, MD and Victor E. Reuter, MD Mixed Mesenchymal and Epithelial Tumors 212 Mixed Epithelial and Stromal Tumor (MEST) Family Tumors Satish K. Tickoo, MD and Victor E. Reuter, MD 220 Pediatric Cystic Nephroma Satish K. Tickoo, MD and Victor E. Reuter, MD 224 Synovial Sarcoma Satish K. Tickoo, MD and Victor E. Reuter, MD Neuroendocrine Tumors 228 Renal Neuroendocrine Tumor/Carcinoid Tumor and Neuroendocrine Carcinoma Satish K. Tickoo, MD and Victor E. Reuter, MD 232 Renal Ewing Sarcoma Satish K. Tickoo, MD and Victor E. Reuter, MD Hematopoietic Tumors 236 Hematopoietic Tumors Satish K. Tickoo, MD, Judy Sarungbam, MD, and Victor E. Reuter, MD Metastatic and Other Tumors 242 Juxtaglomerular Cell Tumor (Reninoma) Satish K. Tickoo, MD and Victor E. Reuter, MD 246 Renomedullary Interstitial Cell Tumor Satish K. Tickoo, MD and Victor E. Reuter, MD 250 Other Rare Tumors Satish K. Tickoo, MD and Victor E. Reuter, MD 258 Metastatic Tumors Satish K. Tickoo, MD and Victor E. Reuter, MD Immunohistochemical Profiles for Tumors Involving Kidney 262 Immunohistochemistry, Kidney Satish K. Tickoo, MD and Victor E. Reuter, MD SECTION 2 Introduction and Overview 270 Classification of Bladder Tumors and Tumor-Like Lesions Steven Christopher Smith, MD, PhD Microscopic Anatomy 272 Microscopic Anatomy of Urinary Bladder Hikmat Al-Ahmadie, MD and Mahul B. Amin, MD 276 Microscopic Anatomy of Urethra Hikmat Al-Ahmadie, MD and Mahul B. Amin, MD 280 Microscopic Anatomy of Ureter Steven Christopher Smith, MD, PhD 282 Microscopic Anatomy of Renal Pelvis Steven Christopher Smith, MD, PhD Nonneoplastic Lesions of Urinary Tract 286 Overview of Cystitis Steven Christopher Smith, MD, PhD 292 Polypoid Cystitis Steven Christopher Smith, MD, PhD 300 Malakoplakia Steven Christopher Smith, MD, PhD 306 Schistosomiasis Steven Christopher Smith, MD, PhD 308 von Brunn Nests Steven Christopher Smith, MD, PhD 314 Nephrogenic Adenoma (Metaplasia) Steven Christopher Smith, MD, PhD 322 Fibroepithelial Polyp Steven Christopher Smith, MD, PhD 326 Prostatic-Type Polyp (Ectopic Prostate) Steven Christopher Smith, MD, PhD 330 Amyloidosis Steven Christopher Smith, MD, PhD 332 Müllerian Lesions Steven Christopher Smith, MD, PhD 336 Pseudocarcinomatous Hyperplasia Steven Christopher Smith, MD, PhD 344 Hamartoma Steven Christopher Smith, MD, PhD Urothelial Neoplasms, General 346 Overview of Urinary Bladder Neoplasms Hikmat Al-Ahmadie, MD Flat Urothelial Lesions 350 Urothelial Carcinoma In Situ Steven Christopher Smith, MD, PhD 358 Flat Urothelial Lesions Other Than Carcinoma In Situ Steven Christopher Smith, MD, PhD UROTHELIAL NEOPLASMS, NONINVASIVE 362 Atypical Urothelial Proliferations, Flat and Tented Type (Formerly Flat and Papillary Hyperplasia) Jatin S. Gandhi, MD and Mahul B. Amin, MD 364 Urothelial Papilloma Steven Christopher Smith, MD, PhD 370 Papillary Urothelial Neoplasm of Low Malignant Potential Steven Christopher Smith, MD, PhD 374 Low-Grade Papillary Urothelial Carcinoma Hikmat Al-Ahmadie, MD 378 High-Grade Papillary Urothelial Carcinoma Hikmat Al-Ahmadie, MD 384 Inverted Urothelial Neoplasia Steven Christopher Smith, MD, PhD Urothelial Neoplasms, Invasive 394 Invasive Urothelial Carcinoma Hikmat Al-Ahmadie, MD 404 Urothelial Carcinoma, Subtypes and Divergent Differentiation Steven Christopher Smith, MD, PhD Glandular Lesions 426 Cystitis Cystica et Glandularis Hikmat Al-Ahmadie, MD 430 Villous Adenoma Hikmat Al-Ahmadie, MD 432 Invasive Adenocarcinoma Hikmat Al-Ahmadie, MD 438 Clear Cell Adenocarcinoma Hikmat Al-Ahmadie, MD Squamous Lesions 444 Squamous Proliferations Other Than Carcinoma Hikmat Al-Ahmadie, MD 448 Invasive Squamous Cell Carcinoma Hikmat Al-Ahmadie, MD Mesenchymal Lesions 454 Myofibroblastic Proliferations Steven Christopher Smith, MD, PhD 462 Smooth Muscle Tumors Steven Christopher Smith, MD, PhD 470 Rhabdomyosarcoma Steven Christopher Smith, MD, PhD 476 Other Mesenchymal Tumors Steven Christopher Smith, MD, PhD Other Tumors of Urinary Bladder 484 Paraganglioma Steven Christopher Smith, MD, PhD 492 Metastatic/Secondary Involvement of Bladder Steven Christopher Smith, MD, PhD Diverticula of Urinary Tract 500 Diverticula Hikmat Al-Ahmadie, MD and Mahul B. Amin, MD 504 Diverticular-Associated Neoplasia Hikmat Al-Ahmadie, MD and Mahul B. Amin, MD URETHRA 508 Inflammatory Lesions of Urethra Steven Christopher Smith, MD, PhD 512 Carcinoma of Urethra Steven Christopher Smith, MD, PhD 516 Other Tumors and Tumor-Like Lesions of Urethra Steven Christopher Smith, MD, PhD URETER 520 Urothelial Carcinoma of Ureter Hikmat Al-Ahmadie, MD 524 Other Tumors and Tumor-Like Lesions of Ureter Hikmat Al-Ahmadie, MD RENAL PELVIS 530 Urothelial Carcinoma of Renal Pelvis Hikmat Al-Ahmadie, MD 540 Other Tumors and Tumor-Like Lesions of Renal elvis Urachs 546 Urachal Remnants Steven Christopher Smith, MD, PhD 548 Tumors of Urachus Immunohistochemical Profiles for Tumors Involving Urinary Bladder 554 Immunohistochemistry, Urinary Tract SECTION 3: PROSTATE GLAND AND SEMINAL VESICLE Introduction and Overview 562 Classification of Prostate Tumors and Tumor-Like Lesions Gladell P. Paner, MD, (BS) MT 564 General Concepts, Prostate 570 Microanatomy and Zonal Variations 580 Imaging Considerations for Pathologists NONNEOPLASTIC LESIONS 584 Prostatitis 588 Prostate Hyperplasia 596 Adenosis Hikmat Al-Ahmadie, MD and Mahul B. Amin, MD 600 Atrophy and Its Patterns 606 Hyperplasia of Mesonephric Remnants 610 Verumontanum Mucosal Gland Hyperplasia Gladell P. Paner, MD, (BS) MT and Deepika Sirohi, MD 612 Nephrogenic Adenoma (Metaplasia) of Prostatic Urethra PUTATIVE PREMALIGNANT LESIONS AND LESIONS FALLING SHORT OF MALIGNANT DIAGNOSIS 620 Prostatic Intraepithelial Neoplasia Prostate Neoplasms 630 General Concepts, Prostate Carcinoma 638 Acinar Adenocarcinoma 656 Acinar Adenocarcinoma Subtypes and Patterns 668 Atypical Small Acinar Proliferations 674 Intraductal Proliferations and Ductal Carcinoma 682 Ductal Adenocarcinoma 690 Urothelial Carcinoma Involving Prostate Gland 696 Prostate Carcinoma With Neuroendocrine Differentiation 704 Adenoid Cystic (Basal Cell) Carcinoma of Prostate 710 Sarcomatoid Carcinoma of Prostate 716 Carcinomas With Squamous Differentiation 722 Cystic Epithelial Tumors of Prostate 724 Stromal Tumors 732 Mesenchymal Tumors of Prostate 740 Melanocytic Lesions of Prostate 744 Hematopoietic Neoplasms of Prostate 748 Secondary Tumors of Prostate Tumors of Seminal Vesicle 752 Mixed Epithelial and Stromal Tumor 756 Seminal Vesicle Adenocarcinoma Immunohistochemical Profiles for Tumors and Tumor-Like Lesions Involving Prostate Gland 758 Immunohistochemistry, Prostate SECTION 4: TESTIS AND PARATESTICULAR STRUCTURES 766 Classification of Testis and Paratestis Tumors and Tumor-Like Lesions Steven S. Shen, MD, PhD, Muhammad T. Idrees, MD, and Jae Y. Ro, MD, PhD 768 Cryptorchidism 772 Sertoli Cell-Only Syndrome Steven S. Shen, MD, PhD and Jae Y. Ro, MD, PhD 776 Nontuberculous Infections 778 Nonspecific Granulomatous Orchitis 780 Tuberculous Epididymo-Orchitis Germ Cell Tumors 782 General Concepts, Germ Cell Tumors Germ Cell Tumors Related to Germ Cell Neoplasia In Situ 790 Germ Cell Neoplasia In Situ 796 Seminoma 804 Intratubular Seminoma 806 Intratubular Embryonal Carcinoma Steven S. Shen, MD, PhD 808 Embryonal Carcinoma 814 Yolk Sac Tumor 822 Choriocarcinoma and Other Trophoblastic Tumors 828 Postpubertal-Type Teratoma 832 Mixed Germ Cell Tumors 836 Somatic-Type Malignancy in Germ Cell Tumor 838 Burnt-Out (Regressed) Germ Cell Tumor Germ Cell Tumors Unrelated to Germ Cell Neoplasia In Situ 840 Spermatocytic Tumor 844 Pediatric Germ Cell Tumor, General Concepts 846 Prepubertal-Type Teratoma 850 Yolk Sac Tumor, Prepubertal Type 854 Mixed Teratoma and Yolk Sac Tumor, Prepubertal Type Muhammad T. Idrees, MD 856 Well-Differentiated Neuroendocrine Tumor (Monodermal Teratoma) Sex Cord-/Gonadal Stromal Tumors 860 General Concepts, Sex Cord-/Gonadal Stromal Tumors Steven S. Shen, MD, PhD, Mukul K. Divatia, MD, and Jae Y. Ro, MD, PhD 868 Leydig Cell Tumors Steven S. Shen, MD, PhD, Muhammad T. Idrees, MD, Mukul K. Divatia, MD, and Jae Y. Ro, MD, PhD 872 Sertoli Cell Tumors 878 Large Cell Calcifying Sertoli Cell Tumor 882 Intratubular Large Cell Hyalinizing Sertoli Cell Tumor Mukul K. Divatia, MD, Steven S. Shen, MD, PhD, and Muhammad T. Idrees, MD 884 Granulosa Cell Tumor Steven S. Shen, MD, PhD, Mukul K. Divatia, MD, and Muhammad T. Idrees, MD 888 Juvenile Granulosa Cell Tumor 892 Fibroma-Thecoma Mukul K. Divatia, MD, Steven S. Shen, MD, PhD, and Jae Y. Ro, MD, PhD 894 Myoid Gonadal Stromal Tumor 896 Signet-Ring Stromal Tumors 898 Testicular Tumor of Adrenogenital Syndrome 902 Sex Cord-Stromal Tumor, Mixed/Unclassified Steven S. Shen, MD, PhD, Mukul K. Divatia, MD, and 906 Gonadoblastoma Hematopoietic Tumors 910 Lymphoma/Leukemia/Plasmacytoma Tumors Of Paratesticular Structures 916 Adenomatoid Tumor Steven S. Shen, MD, PhD, Jae Y. Ro, MD, PhD, and Muhammad T. Idrees, MD 920 Well-Differentiated Papillary Mesothelial Tumor 922 Malignant Mesothelioma 926 Adenocarcinoma of Rete Testis/Epididymis 928 Epididymal Tumors 930 Ovarian Epithelial-Type Tumors 934 Liposarcoma 940 Melanotic Neuroectodermal Tumor 944 Rhabdomyosarcoma 950 Other Sarcomas Metastatic Tumors, Testis and Paratesticular Structures 954 Metastatic Tumors, Testis and Paratesticular Structures Immunohistochemical Profiles for Tumors Involving Testis and Paratesticular Structures 958 Immunohistochemistry, Testis SECTION 5: PENIS AND SCROTUM Frequent Lesions of Uncertain Relationship to Penile Neoplasia 968 Condyloma María José Fernández De Nestosa, PhD 972 Lichen Sclerosus et Atrophicus Elsa F. Velazquez, MD, Sofía Cañete-Portillo, MD, and Antonio L. Cubilla, MD 974 Squamous Hyperplasia Sofía Cañete-Portillo, MD, Diego Fernando Sánchez Martínez, MD, and Antonio L. Cubilla, MD 978 Lipogranuloma Elsa F. Velazquez, MD and Antonio L. Cubilla, MD 980 Scrotal Calcinosis Penile Intraepithelial Neoplasia 982 Penile Intraepithelial Neoplasia Elsa F. Velazquez, MD, Diego Fernando Sánchez Martínez, MD, and Antonio L. Cubilla, MD Primary Epithelial Tumors 988 General Concepts, Squamous Cell Carcinoma (Including Staging and Molecular Pathology) Antonio L. Cubilla, MD, Diego Fernando Sánchez Martínez, MD, Sofía Cañete-Portillo, MD, Mahul B. Amin, MD, and Elsa F. Velazquez, MD 1002 Overview of HPV- and Non-HPV-Related Tumors María José Fernández De Nestosa, PhD, Diego Fernando Sánchez Martínez, MD, Mahul B. Amin, MD, and Antonio L. Cubilla, MD Squamous Cell Carcinoma and Its Subtypes 1006 Squamous Cell Carcinoma, Usual Type Antonio L. Cubilla, MD, Diego Fernando Sánchez Martínez, MD, and Sofía Cañete-Portillo, MD 1010 Basaloid Squamous Cell Carcinoma 1014 Basaloid Squamous Cell Carcinoma, Papillary Subtype Diego Fernando Sánchez Martínez, MD and Antonio L. Cubilla, MD 1016 Warty (Condylomatous) Squamous Cell Carcinoma 1020 Warty-Basaloid Squamous Cell Carcinoma 1022 Verrucous Squamous Cell Carcinoma 1026 Papillary Squamous Cell Carcinoma, Not Otherwise Specified 1030 Pseudoglandular Squamous Cell Carcinoma 1032 Pseudohyperplastic Squamous Cell Carcinoma 1034 Cuniculatum Squamous Cell Carcinoma 1038 Sarcomatoid Squamous Cell Carcinoma 1042 Mixed Squamous Cell Carcinoma 1046 Undifferentiated to Poorly Differentiated Squamous Cell Carcinomas With Prominent Inflammatory Infiltrate 1048 Clear Cell Carcinoma Other Neoplastic Conditions 1050 Extramammary Paget Disease 1054 Kaposi Sarcoma Elsa F. Velazquez, MD, Jesse K. McKenney, MD, and Antonio L. Cubilla, MD 1056 Myointimoma Mahul B. Amin, MD and Jatin S. Gandhi, MD Metastatic Tumors 1058 Metastatic Tumors, Penis Immunohistochemical Profiles for Tumors Involving Penis 1060 Immunohistochemistry, Penis

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