Preface. List of Contributors. Part I: Glial Cell Development. 1. Developmental regulation in the Schwann cell lineage; K.R. Jessen, R. Mirsky. 2. Transcriptional regulation of the POU gene Oct-6 in Schwann cells; W. Mandemakers, et al. 3. Glia development in the embryonic CNS of Drosophila; C. Klambt, et al. 4. Role and mechanism of action of glial cell deficient/glial cell missing (glide/gcm), the fly glial promoting factor; A.A. Miller, et al. Part II: Glia in Neurotransmission, Neuromodulation and Neuron Survival. 5. Expression and functional analysis of glutamate receptors in glial cells; D.F. Condorelli, et al. 6. Astrocytes as active participants of glutamatergic function and regulators of its homeostasis; P. Bezzi, et al. 7. Glia-neuron interaction by high-affinity glutamate transporters in neurotransmission; T. Rauen, et al. 8. On how altered glutamate homeostasis may contribute to demyelinating diseases of the CNS; C. Matute, et al. 9. Possible role of microglial prostanoids and free radicals in neuroprotection and neurodegeneration; L. Minghetti, et al. Part III: Glia, Inflammation and Cytokines. 10. The role of microglia and astrocytes in CNS immune surveillance and immunopathology; F. Aloisi. 11. The role of chemokines in the pathogenesis of multiple sclerosis; M.N. Woodroofe, et al. 12. Humoral and cellular immune functions of cytokine-treated Schwann cells; G. Wohlleben, et al. 13. Axotomy-induced glial reactions in normal and cytokine transgenic mice; B. Finsen, et al. Part IV: Glia in CNS Plasticity and Regeneration. 14. Contribution of astrocytes to activity-dependent structural plasticity in the adult brain; D.T. Theodosis, et al. 15. The role of oligodendrocytes and oligodendrocyte progenitors in CNS remyelination; H.S. Keirstead, W.F. Blakemore. 16. Growth promoting and inhibitory effects of glial cells in the mammalian nervous system; S. Hirsch, M. Bähr. 17. Neurite outgrowth inhibitors in gliotic tissue; M. Nieto-Sampedro. Part V: Transgenic Models of Human Myelin Diseases. 18. Connexin32 in hereditary neuropathies; D.H.H. Neuberg, U. Suter. 19. Genetic analysis of myelin galactolipid function; B. Popko, et al. 20. Transgenic models of TNF-induced demyelination; K. Akassoglou, et al. 21. Dysmyelination in mice and the proteolipid protein gene family; L. Dimou, et al. Part VI: Neuron-glial Communication: Neurotrophins and Cell Adhesion Molecules. 22. Neurotrophins in cell survival/death decisions; P. Casaccia-Bonnefil, et al. 23. Neuregulin in neuron/glial interactions in the central nervous system: GGF2 diminishes autoimmune demyelination, promotes oligodendrocyte progenitor expansion and enhances remyelination; M.A. Marchionni, et al. 24. Adhesion molecule expression and phenotype of glial cells in the olfactory tract; S.C. Barnett, I.A. Franceschini. 25. Bidirectional signaling between neurons and glial cells via the F3 neuronal adhesion molecule; J.-M. Revest. Part VII: Connexins and Information Transfer Through Glia. 26