Advances in Chemical Proteomics

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2021
ISBN13: 9780128214336
Rubricering
Elsevier Science e druk, 2021 9780128214336
Onderdeel van serie Developments in Organic Chemistry
€ 237,40
Levertijd ongeveer 8 werkdagen

Samenvatting

Advances in Chemical Proteomics provides essential concepts and recent applications on probes, tool compounds and concepts for chemical proteomics and then moves on to applications, including solid-phase reagents, fragment screening, designer compounds and protein lipidation. As the second volume in the Developments in Organic Chemistry series, each chapter is written by experts in the field. Users will find this to be a valuable reference for organic chemists and chemical biologists who are interested in developing tool compounds and reagents to measure and interrogate proteome, develop drug leads, and measure off-target effects and drug toxicity.

Analytical chemists who are interested in better understanding organic chemistry behind commonly used reagents for quantitative proteomics and tools compounds in the emerging field of chemical proteomics will also benefit from this comprehensive resource on the topics presented.

Specificaties

ISBN13:9780128214336
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>1. Tool compounds for mass spectrometry-based chemical proteomics<br>2. Principles of proteomic reactions of covalent inhibitors<br>3. Reporter tags and chemistry for probe-reacted proteins<br>4. Chemical derivatization of peptides for quantitative proteomics<br>5. Database-searching strategies for probe-reacted proteins in a proteome<br>6. Solid-phase reagents for discovering inhibitors of kinases<br>7. Fragment screening for discovering covalent probes<br>8. Designer compounds for locational proteomics<br>9. Chemical proteomics for exploring protein lipidation Targeting Author: Edward Tate<br>10. Synthetic evolution of indocyanine green with the 2-nitroimidazole warhead for imaging of hypoxic tumor</p>
€ 237,40
Levertijd ongeveer 8 werkdagen

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        Advances in Chemical Proteomics