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Translational Gastroenterology

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2025
ISBN13: 9780128214268
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Elsevier Science e druk, 2025 9780128214268
€ 172,60
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Samenvatting

Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.

The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

Specificaties

ISBN13:9780128214268
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>PART I: CONCEPT<br>1. Introduction to clinical research<br>2. The question<br>3. Study population<br>4. Outcome measurements<br><br>PART II: STUDY TYPES<br>5. Design principles<br>6. Case series<br>7. Case-control study<br>8. Cohort study<br>9. Cross-section study<br>10. Clinical trials<br>11. Meta-analysis<br>12. Cost-effectiveness study<br>13. Diagnostic test evaluation<br>14. Reliability study<br>15. Database studies<br>16. Surveys and questionnaires<br>17. Qualitative methods and mixed methods Definition of the study type<br><br>PART III: CLINICAL TRIALS<br>17. Randomized control<br>18. Nonrandomized control<br>19. Historical control<br>20. Cross-over<br>21. Withdrawal studies<br>22. Factorial design<br>23. Group allocation<br>24. Hybrid design<br>25. Large, pragmatic<br>26. Equivalence and noninferiority<br>27. Adaptive<br>28. Randomization<br>30. Multicenter considerations Study design and practical considerations<br><br>PART IV: PLANNING<br>31. Optimizing the question<br>32. Meaningful outcome measurements  <br>33. Sample size Power analysis<br>34. Budgeting Funding, timeline, personnel, materials<br>35. Ethics and review boards <br>36. Regulatory considerations for new drugs and devices <br>37. Funding approaches  <br>38. Research team <br>39. Subject recruitment  <br>40. Data management  <br>41. Quality control  <br>42. Report forms<br>43. Subject adherence  <br>44. Survival analysis  <br>45. Monitoring committee in clinical trials<br><br>PART V: STATISTICAL PRINCIPLES<br>46. Presenting data  <br>47. Common issues in analysis  <br>48. Basic statistical principles  <br>49. Distributions Description, examples, implications in analysis. <br>50. Hypotheses and error types  <br>51. Power Detecting effects<br>52. Regression Explanation<br>53. t-test Explanation<br>54. Chi-square Explanation<br>55. Analysis of variance Explanation<br>56. Correlation Explanation<br>57. Biases </p>
€ 172,60
Levertijd ongeveer 8 werkdagen

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        Translational Gastroenterology