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Nutraceuticals

Efficacy, Safety and Toxicity

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2021
ISBN13: 9780128210383
Rubricering
Elsevier Science e druk, 2021 9780128210383
€ 211,00
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Samenvatting

Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered.

Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.

Specificaties

ISBN13:9780128210383
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Section I. Applications of nutraceuticals in common diseases and disorders <br>1. Nutraceuticals in central nervous system diseases: potential mechanisms of neuroprotection <br>2. Prevention of neurodegenerative disorders by nutraceuticals <br>3. Cognitive effects of nutraceuticals <br>4. Nutraceuticals in anxiety and stress <br>5. Countering cardiovascular diseases with nutraceuticals <br>6. Nutraceuticals for diabetes and glucose balance <br>7. Role of nutraceuticals in respiratory and allied diseases <br>8. Nutraceuticals in hepatic diseases <br>9. Nutraceuticals in renal diseases <br>10. Nutraceuticals in gastrointestinal disorders <br>11. Nutraceuticals in reproductive and developmental disorders <br>12. Nutraceuticals in ophthalmic diseases <br>13. Nutraceuticals in dermal diseases<br>14. Nutraceuticals in arthritis <br>15. Nutraceuticals in sports activities and fatigue <br>16. Role of nutraceuticals as adaptogens <br>17. Nutraceuticals for weight loss <br>18. Nutraceuticals in cancer prevention<br>19. Application of “nano” nutraceuticals in medicine <br>Section II. Models and mechanisms in evaluation of nutraceuticals <br>20. The biology of nutrients: genetic and molecular principles <br>21. Genomic and proteomic mechanisms and models in toxicity and safety evaluation of nutraceuticals <br>22. Transcriptomic profiling for safety and toxicity evaluation of<br>nutraceuticals <br>23. Target identification and polypharmacology of nutraceuticals <br>24. Systems pharmacology investigation of mechanism of action of nutraceuticals<br>25. Noninvasive in vivo optical imaging models for safety and toxicity testing <br>26. Flow cytometry and light-scattering techniques in evaluation of nutraceuticals <br>27. Zebrafish as a model system to evaluate the safety and toxicity of nutraceuticals<br>28. Caenorhabditis elegans: an elegant model organism for evaluating the neuroprotective and neurotherapeutic potential of nutraceuticals <br>29. Alternative in vitro models for safety and toxicity evaluation of nutraceuticals<br>30. Mitochondria as a target for safety and toxicity evaluation of nutraceuticals<br>31. Oxidative stress and excitotoxicity: antioxidants from nutraceuticals<br>Section III. Common nutraceuticals<br>32. Caffeine: an evaluation of the safety database <br>33. Biological activities and potential nanotechnological delivery of resveratrol <br>34. Melatonin: a safe nutraceutical and clinical agent<br>35. Standardized turmeric and curcumin <br>36. Curcuminoid-metal complexes for oxidative stress<br>37. Fenugreek: multiple health benefits<br>38. Cannabis sativa: an overview<br>39. Cannabidiol safety<br>40. St John’s wort (Hypericum perforatum L)<br>41. Green tea <br>42. Green coffee beans<br>43. Quercetin<br>44. German chamomile <br>45. Isoflavones: toxicological aspects and efficacy  <br>46. Propolis <br>47. Bee products as nutraceuticals to nutraceuticals for bees <br>48. Ginkgo biloba <br>49. Chinese ginseng <br>50. Ashwagandha: multiple health benefits <br>51. Astaxanthin: health benefits and toxicity <br>52. Thymoquinone <br>53. Glucosinolates<br>54. Organosulfur compounds as nutraceuticals<br>55. Arginine and citrulline as nutraceuticals: efficacy and safety in diseases <br>56. Neem Extract<br>57. Spirulina <br>58. Garcinia cambogia <br>59. Vitamin E TPGS and its applications in nutraceuticals<br>60. Role of transferrin: an iron-binding protein in health and diseases <br>61. Glutamine supplementation: hope, hype, or stay tuned? <br>62. What to do with placenta after birth: is it a waste? <br>63. Chitin, chitosan, and their derivatives <br>Section IV. Prebiotics and probiotics <br>64. Prebiotics: safety and toxicity considerations<br>65. Probiotics: safety and toxicity considerations<br>66. Synbiotics: safety and toxicity considerations <br>Section V. Nutraceuticals in veterinary medicine <br>67. Nutraceuticals in animal health and diseases <br>Section VI. Toxicity and toxic interactions <br>68. Toxic contamination of nutraceuticals and food ingredients <br>69. Nutraceuticals and adverse outcome pathways <br>70. Interactions between nutraceuticals/nutrients and nutrients and therapeutic drugs <br>71. Genotoxicity evaluation of nutraceuticals <br>Section VII. Regulatory aspects <br>72. The regulatory framework for nutraceuticals: North America<br>73. Evaluation and regulation of food supplements: European perspective<br>74. Regulatory guidelines for nutraceuticals in India: an overview <br>75. Regulatory aspects of nutraceuticals: Chinese perspective<br>76. Uses and regulation of nutraceuticals: Australia and New Zealand <br>77. Regulatory aspects of nutraceuticals: Japanese perspective<br>78. Nutraceuticals: the Turkish perspective </p>
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