Handbook of Innovations in Central Nervous System Regenerative Medicine

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2020
ISBN13: 9780128180846
Rubricering
Elsevier Science e druk, 2020 9780128180846
Verwachte levertijd ongeveer 8 werkdagen

Samenvatting

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path.

Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues.

Specificaties

ISBN13:9780128180846
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. Insights on Nervous System Biology and Anatomy<br>2. Introduction to Neurodegenerative Diseases<br>3. Introduction to Trauma in CNS<br>4. Impact of Neuro-inflammation in Injury and Disease in the CNS<br>5. Current Clinical Approaches in Neurodegenerative Diseases<br>6. Neuroprotection in the Injured Spinal Cord<br>7. Immunomodelatory Approaches for Tackling Neuro-Inflammation<br>8. Role of Fetal and Adult Tissues in CNS Regenerative Medicine<br>9. Adult Stem Cells' Therapeutic Potential for Injured CNS<br>10. iPSCs: An Essential Toolkit for Repair and Regeneration of the CNS?<br>11. Biomaterial-Based Systems as Biomimetic Agents in the Repair of the CNS<br>12. Tissue Engineering and Regenerative Medicine in CNS Repair<br>13. New Trends in Drug Delivery in CNS Regeneration<br>14. Gene Therapy Approaches in CNS Regenerative Medicine<br>15. Gene Editing and CNS Regeneration<br>16. Molecular Therapies in Neurodegeneration and Injury<br>17. Deep Brain Stimulation and Parkinson's Disease<br>18. Brain-Spinal Cord Interfaces<br>19. Electroceuticals<br>20. Secretome of Cells and Its Role in Neuroregeneration<br>21. 3D Organoids and Bioreactors<br>22. Microfluidics and Lab-on-a-Chip<br>23. Translational Research: From Proof of Concept to Clinical Trials<br>24. Advanced Therapies Medicinal Products<br>25. Animal Models of CNS Disorders<br>26. Bioethics in Translation Research and Clinical Trials

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        Handbook of Innovations in Central Nervous System Regenerative Medicine