Glen L. Niebur,
Glen L. (Professor of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN) Niebur
Elsevier Science
e druk, 2019
9780128179314
Mechanobiology
From Molecular Sensing to Disease
Specificaties
Paperback, blz.
|
Engels
Elsevier Science |
e druk, 2019
ISBN13: 9780128179314
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology.
Specificaties
Inhoudsopgave
<p>Section 1: Mechanobiological basis of diseases1.1 Osteoporosis1.2 Cardiovascular mechanics and disease1.3 Glaucoma and eye diseases1.4 Growth and development1.5 Tissue engineering and regenerative medicine</p> <p>Section 2: Cellular basis of Mechanobiology 2.1 Cells as strain gages and load cells2.2 Cell – extracellular matrix interactions2.3 Mechanobiological pathways2.4 Mechanically mediated epigenetics</p> <p>Section 3: Experimental methods3.1 Effects of shear stress on cells3.2 Three-dimensional culture systems3.3 Bioreactors3.4 Tissue and organ on a chip systems</p> <p>Section 4: Computational simulations in mechanobiology4.1 Cell aggregation4.2 Growth models5. Future prospects and challenges6. Bibliography7. Glossary</p>