Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

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Gebonden, blz. | Engels
Elsevier Science | e druk, 2020
ISBN13: 9780128179291
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Elsevier Science e druk, 2020 9780128179291
€ 162,25
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Samenvatting

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.

Specificaties

ISBN13:9780128179291
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. Fluorescence microscopy methods for the study of protein oligomerization<br>Roberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia<br>2. Computational prediction and redesign of aberrant protein oligomerization<br>Jaime Santos, Valentín Iglesias and Salvador Ventura<br>3. Porphobilinogen synthase: An equilibrium of different assemblies in human health<br>Eileen K. Jaffe<br>4. Prediction and targeting of GPCR oligomer interfaces<br>Carlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira<br>5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomers<br>Francesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas<br>6. Exploring functional consequences of GPCR oligomerization requires a different lens<br>Kyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert<br>7. Continuing challenges in targeting oligomeric GPCR-based drugs<br>Joaquin Botta, Julia Appelhans and Peter J. McCormick<br>8. Adenosine A<SUB>2A</SUB>-dopamine D<SUB>2</SUB> receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives<br>Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati<br>9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action<br>Faron-Górecka Agata, Kuśmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta<br>10. Oligomerization of G protein-coupled receptors: Still doubted?<br>Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo</p>
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        Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors