CRISPR Genome Surgery in Stem Cells and Disease Tissues

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2021
ISBN13: 9780128178768
Rubricering
Elsevier Science e druk, 2021 9780128178768
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.

Specificaties

ISBN13:9780128178768
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>1. History of CRISPR<br>2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.) <br>3. Genome engineering in iPSC cells <br>4. CRISPR manipulations in stem cell lines for neurological diseases<br>5. Gene editing for the cornea<br>6. CRISPR screening for eye diseases<br>7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration<br>8. Ethics of Gene Editing in Human Stem Cells <br>9. sGRNA<br>10. CRISPR vs ZFN/TALEN</p>

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        CRISPR Genome Surgery in Stem Cells and Disease Tissues