Behavioral and Neural Genetics of Zebrafish

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2020
ISBN13: 9780128175286
Rubricering
Elsevier Science e druk, 2020 9780128175286
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions.

Specificaties

ISBN13:9780128175286
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Section I. Introduction to Zebrafish: Natural Habitat, Ethology, and Appropriate Maintenance Conditions<br>1. The biotic and abiotic environment of zebrafish <br>2. Maintenance and breeding of zebrafish, with some ethological and ecological considerations in mind</p> <p>Section II. The Behavior of the Fry<br>3. The larval visual system and behavioral responses to visual stimuli<br>4. Visual escape in larval zebrafish: Stimuli, circuits, and behavior<br>5. Functional review of hearing in zebrafish<br>6. The development of social behavior<br>7. Classical and operant conditioning in larval zebrafish</p> <p>Section III. The Behavior of the Adult<br>8. Motor patterns and swim path characteristics: the ethogram of zebrafish<br>9. Behavioral criteria and techniques to define sleep in zebrafish<br>10. Fear responses and antipredatory behavior of zebrafish: A translational perspective<br>11. Social behavior and its psychopharmacological and genetic analysis in zebrafish<br>12. Associative and non-associative learning in adult zebrafish<br>13. Relational learning in zebrafish: A model of declarative memory in humans?</p> <p>Section IV. Genetic Methods for Zebrafish<br>14. Molecular genetic approaches to dissect complex behaviors in zebrafish<br>15. Behavioural research in zebrafish (Danio rerio): strain as source of variation<br>16. Designer mutants for behavioral genetics<br>17. Optogenetics<br>18. The CRISPR/Cas system in zebrafish<br>19. PhOTO Zebrafish and primed conversion: Advancing the mechanistic view of development and disease</p> <p>Section V. Disease Models and Behavior Genetic Applications<br>20. Acute and chronic alcohol effects in zebrafish<br>21. Behavioural genetics of embryonic ethanol exposure in zebrafish: A model for FASD<br>22. Life, death, and regeneration of zebrafish dopaminergic neurons<br>23. Parkinson's Disease<br>24. Seizures and epilepsy<br>25. Aging, circadian clock and neurogenesis: the zebrafish approach<br>26. Modeling autism spectrum disorders in zebrafish<br>27. Studying aggression in zebrafish<br>28. Methylmercury induces transgenerationally transmissible epigenetic changes influencing zebrafish behavior</p> <p>Section VI. Big Data and Bioinformatics<br>29. The design of behavioral screening in zebrafish<br>30. Software tools for behavioral phenotyping of zebrafish across the life span<br>31. The Zebrafish Genome Sequencing Project: Bioinformatics resources<br>32. Registered, standardized, and interactive: a review of online resources for zebrafish neuroanatomy</p>

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        Behavioral and Neural Genetics of Zebrafish