<p>PART I: INTRODUCTORY CHAPTERS<br>1. Becoming a "Successful" Drinker and a Graduate: A Sociological Perspective on Alcohol Consumption by University Students<br>2. Molecular Genetics Meets Sociology: Birth Cohort Effects on Alcohol Use and Relationship With Candidate Genes<br>3. Alcohol and Women: Unique Risks, Effects, and Implications for Clinical Practice<br>4. ADH and ALDH Polymorphisms in Alcoholism and Alcohol Misuse/Dependence<br>5. Acetaldehyde in the Brain After Ethanol Exposure: Research Progress and Challenges<br>6. Consequences of Ethanol Exposure on Neurodevelopment<br>7. Animal Models of Binge Drinking: Behavior and Clinical Relevance</p> <p>PART II: NEUROBIOLOGY<br>8. Prenatal Alcohol Exposure: Developmental Abnormalities in the Brain<br>9. Connecting Prenatal Alcohol, Its Metabolite Acetaldehyde, and the Fetal Brain<br>10. Fetal Alcohol Exposure and the Central Nervous Control of Breathing<br>11. Synaptic Plasticity in the Hippocampus and Alcohol Exposure During Brain Development<br>12. Ethanol and Cortical Spreading Depression: The Protective Role of α-Tocopherol<br>13. Brain Electrophysiological Signatures in Human Alcoholism and Risk<br>14. Alcohol and Hippocampal Epileptiform Activity<br>15. Effects of Alcohol on the Corpus Callosum<br>16. The Role of the Lateral Habenula Circuitries in Alcohol Use Disorders<br>17. Ventral Pallidum and Alcohol Addiction<br>18. The Hyperpolarization-Activated Cyclic Nucleotide-Gated Ion Channels in the Rewarding Effects of Ethanol<br>19. Neuroimmune Aspects of Alcoholism and Affective Comorbidity<br>20. Social Drinking and Motor Inhibition: Evidences From FMRI Go/Nogo Tasks fMRI Studies on Alcohol Effect on Inhibition<br>21. Myelopathy and Neuropathy Associated With Alcoholism<br>22. Alcohol Consumption and the Risk of Amyotrophic Lateral Sclerosis<br>23. Alcohol and Pain Interactions<br>24. Neurobiological Aspects of Ethanol-Derived Salsolinol<br>25. Brain Networks in Active Alcoholism and Enduring Recovery: Functional Magnetic Resonance Imaging, Electrophysiological Studies, and Implications for Targeted Treatments<br>26. Central Role of Amygdala and Hypothalamus Neural Circuits in Alcohol Withdrawal Symptom</p> <p>PART III: PSYCHOLOGY, BEHAVIOR, AND ADDICTION<br>27. Neural Reward Processing in Human Alcoholism and Risk: A Focus on Event-Related Potentials, Oscillations, and Neuroimaging<br>28. Occipito-Temporal Sensitivity and Emotional Faces in Alcohol Use Disorder<br>29. Alcohol and Violence in Psychopathy and Antisocial Personality Disorder: Neural Mechanisms<br>30. Language Lateralization in Fetal Alcohol Spectrum Disorders<br>31. Deprivation in Rewards and Alcohol Misuse<br>32. Alcohol (Mis)Use in Individuals With Mild to Borderline Intellectual Disability<br>33. Sex, Stress, and Neuropeptides Interact to Influence Alcohol Consumption<br>34. Maternal Separation Stress in Fetal Alcohol Spectrum Disorders: A Case of Double Whammy<br>35. Impulsivity and Binge Drinking: A Neurocognitive Perspective<br>36. Acetaldehyde and Motivation<br>37. Age-Related Differences in the Appetitive and Aversive Motivational Effects of Alcohol<br>38. Alcoholism in Bipolar Disorders: An Overview of Epidemiology, Common Pathogenetic Pathways, Course of Disease, and Implications for Treatment<br>39. Socio-Emotional Deficits in Severe Alcohol Use Disorders<br>40. Relapse Risks in Patients With Alcohol Use Disorders<br>41. The Neurocognitive Effects of Alcohol Hangover: Patterns of Impairment/Nonimpairment Within the Neurocognitive Domains of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition</p> <p>PART IV: PHARMACOLOGY, NEUROACTIVES, MOLECULAR, AND CELLULAR BIOLOGY<br>42. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk<br>43. Alcohol’s Effects on Extracellular Striatal Dopamine<br>44. Nicotinic Cholinergic Mechanisms in Alcohol Abuse and Dependence<br>45. Opioid System and Alcohol Consumption<br>46. The Enkephalinergic System and Ethanol Effects<br>47. Alcohol and Central Glutamate Activity: What Goes Up Must Come Down?<br>48. Ethanol and Hippocampal Gene Expression: Linking in Ethanol Metabolism, Neurodegeneration, and Resistance to Oxidative Stress<br>49. Stress, Alcohol, and Hippocampal Genes<br>50. Genes and Alcoholism: Taste, Addiction, and Metabolism<br>51. Ethanol Exposure During Development, and Brain Oxidative Stress<br>52. Alcohol-Induced Oxidative Stress in the Brain: Suggested Mechanisms, Associated Disorders, and Therapeutic Strategies<br>53. Lead Exposure and Ethanol Intake: Oxidative Stress as a Converging Mechanism of Action</p> <p>PART V: ALCOHOL AND OTHER ADDICTIONS<br>54. Alcohol and Gambling Addiction<br>55. Neuroscience of Alcohol and Crack Cocaine Use: Metabolism, Effects and Symptomatology<br>56. The Impact of Ethanol Plus Caffeine Exposure on Cognitive, Emotional, and Motivational Effects Related to Social Functioning</p> <p>PART VI: BIOMARKERS AND SCREENING<br>57. Biomarkers of Alcohol Misuse<br>58. Phosphatidylethanol Homologs in Blood as Biomarkers for the Time Frame and Amount of Recent Alcohol Consumption<br>59. Metabolomics to Differentiate Alcohol Use Disorders From Social Drinkers and Alcohol-Naive Subjects<br>60. Meconium Biomarkers of Prenatal Alcohol Exposure<br>61. Applications of the Alcohol Use Disorders Identification Test (AUDIT) in Distinct Health Areas <br>62. Craving Measurement and Application of the Alcohol Craving Experience Questionnaire</p> <p>PART VII: TREATMENTS, STRATEGIES AND RESOURCES<br>63. Negative Emotions and Alcohol Use Disorder Treatment<br>64. Use of Baclofen in Alcohol Use Disorder: A Clinical Approach<br>65. Baclofen-Induced Neurotoxicity<br>66. Treatment With Nalmefene in Alcoholism<br>67. Dual Therapy for Alcohol Use Disorders: Combining Naltrexone With Other Medications<br>68. The Avermectin Family as Potential Therapeutic Compounds for Alcohol Use Disorder: Implications for Using P2X4 Receptor as a Drug-Screening Platform<br>69. Alcohol Withdrawal Syndrome: Clinical Picture and Therapeutic Options<br>70. Resources for the Neuroscience of Alcohol</p>