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Neuroscience of Alcohol

Mechanisms and Treatment

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2019
ISBN13: 9780128131251
Rubricering
Elsevier Science e druk, 2019 9780128131251
€ 263,80
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Samenvatting

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse.

Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance.

Specificaties

ISBN13:9780128131251
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>PART I: INTRODUCTORY CHAPTERS<br>1. Becoming a "Successful" Drinker and a Graduate: A Sociological Perspective on Alcohol Consumption by University Students<br>2. Molecular Genetics Meets Sociology: Birth Cohort Effects on Alcohol Use and Relationship With Candidate Genes<br>3. Alcohol and Women: Unique Risks, Effects, and Implications for Clinical Practice<br>4. ADH and ALDH Polymorphisms in Alcoholism and Alcohol Misuse/Dependence<br>5. Acetaldehyde in the Brain After Ethanol Exposure: Research Progress and Challenges<br>6. Consequences of Ethanol Exposure on Neurodevelopment<br>7. Animal Models of Binge Drinking: Behavior and Clinical Relevance</p> <p>PART II: NEUROBIOLOGY<br>8. Prenatal Alcohol Exposure: Developmental Abnormalities in the Brain<br>9. Connecting Prenatal Alcohol, Its Metabolite Acetaldehyde, and the Fetal Brain<br>10. Fetal Alcohol Exposure and the Central Nervous Control of Breathing<br>11. Synaptic Plasticity in the Hippocampus and Alcohol Exposure During Brain Development<br>12. Ethanol and Cortical Spreading Depression: The Protective Role of α-Tocopherol<br>13. Brain Electrophysiological Signatures in Human Alcoholism and Risk<br>14. Alcohol and Hippocampal Epileptiform Activity<br>15. Effects of Alcohol on the Corpus Callosum<br>16. The Role of the Lateral Habenula Circuitries in Alcohol Use Disorders<br>17. Ventral Pallidum and Alcohol Addiction<br>18. The Hyperpolarization-Activated Cyclic Nucleotide-Gated Ion Channels in the Rewarding Effects of Ethanol<br>19. Neuroimmune Aspects of Alcoholism and Affective Comorbidity<br>20. Social Drinking and Motor Inhibition: Evidences From FMRI Go/Nogo Tasks fMRI Studies on Alcohol Effect on Inhibition<br>21. Myelopathy and Neuropathy Associated With Alcoholism<br>22. Alcohol Consumption and the Risk of Amyotrophic Lateral Sclerosis<br>23. Alcohol and Pain Interactions<br>24. Neurobiological Aspects of Ethanol-Derived Salsolinol<br>25. Brain Networks in Active Alcoholism and Enduring Recovery: Functional Magnetic Resonance Imaging, Electrophysiological Studies, and Implications for Targeted Treatments<br>26. Central Role of Amygdala and Hypothalamus Neural Circuits in Alcohol Withdrawal Symptom</p> <p>PART III: PSYCHOLOGY, BEHAVIOR, AND ADDICTION<br>27. Neural Reward Processing in Human Alcoholism and Risk: A Focus on Event-Related Potentials, Oscillations, and Neuroimaging<br>28. Occipito-Temporal Sensitivity and Emotional Faces in Alcohol Use Disorder<br>29. Alcohol and Violence in Psychopathy and Antisocial Personality Disorder: Neural Mechanisms<br>30. Language Lateralization in Fetal Alcohol Spectrum Disorders<br>31. Deprivation in Rewards and Alcohol Misuse<br>32. Alcohol (Mis)Use in Individuals With Mild to Borderline Intellectual Disability<br>33. Sex, Stress, and Neuropeptides Interact to Influence Alcohol Consumption<br>34. Maternal Separation Stress in Fetal Alcohol Spectrum Disorders: A Case of Double Whammy<br>35. Impulsivity and Binge Drinking: A Neurocognitive Perspective<br>36. Acetaldehyde and Motivation<br>37. Age-Related Differences in the Appetitive and Aversive Motivational Effects of Alcohol<br>38. Alcoholism in Bipolar Disorders: An Overview of Epidemiology, Common Pathogenetic Pathways, Course of Disease, and Implications for Treatment<br>39. Socio-Emotional Deficits in Severe Alcohol Use Disorders<br>40. Relapse Risks in Patients With Alcohol Use Disorders<br>41. The Neurocognitive Effects of Alcohol Hangover: Patterns of Impairment/Nonimpairment Within the Neurocognitive Domains of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition</p> <p>PART IV: PHARMACOLOGY, NEUROACTIVES, MOLECULAR, AND CELLULAR BIOLOGY<br>42. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk<br>43. Alcohol’s Effects on Extracellular Striatal Dopamine<br>44. Nicotinic Cholinergic Mechanisms in Alcohol Abuse and Dependence<br>45. Opioid System and Alcohol Consumption<br>46. The Enkephalinergic System and Ethanol Effects<br>47. Alcohol and Central Glutamate Activity: What Goes Up Must Come Down?<br>48. Ethanol and Hippocampal Gene Expression: Linking in Ethanol Metabolism, Neurodegeneration, and Resistance to Oxidative Stress<br>49. Stress, Alcohol, and Hippocampal Genes<br>50. Genes and Alcoholism: Taste, Addiction, and Metabolism<br>51. Ethanol Exposure During Development, and Brain Oxidative Stress<br>52. Alcohol-Induced Oxidative Stress in the Brain: Suggested Mechanisms, Associated Disorders, and Therapeutic Strategies<br>53. Lead Exposure and Ethanol Intake: Oxidative Stress as a Converging Mechanism of Action</p> <p>PART V: ALCOHOL AND OTHER ADDICTIONS<br>54. Alcohol and Gambling Addiction<br>55. Neuroscience of Alcohol and Crack Cocaine Use: Metabolism, Effects and Symptomatology<br>56. The Impact of Ethanol Plus Caffeine Exposure on Cognitive, Emotional, and Motivational Effects Related to Social Functioning</p> <p>PART VI: BIOMARKERS AND SCREENING<br>57. Biomarkers of Alcohol Misuse<br>58. Phosphatidylethanol Homologs in Blood as Biomarkers for the Time Frame and Amount of Recent Alcohol Consumption<br>59. Metabolomics to Differentiate Alcohol Use Disorders From Social Drinkers and Alcohol-Naive Subjects<br>60. Meconium Biomarkers of Prenatal Alcohol Exposure<br>61. Applications of the Alcohol Use Disorders Identification Test (AUDIT) in Distinct Health Areas <br>62. Craving Measurement and Application of the Alcohol Craving Experience Questionnaire</p> <p>PART VII: TREATMENTS, STRATEGIES AND RESOURCES<br>63. Negative Emotions and Alcohol Use Disorder Treatment<br>64. Use of Baclofen in Alcohol Use Disorder: A Clinical Approach<br>65. Baclofen-Induced Neurotoxicity<br>66. Treatment With Nalmefene in Alcoholism<br>67. Dual Therapy for Alcohol Use Disorders: Combining Naltrexone With Other Medications<br>68. The Avermectin Family as Potential Therapeutic Compounds for Alcohol Use Disorder: Implications for Using P2X4 Receptor as a Drug-Screening Platform<br>69. Alcohol Withdrawal Syndrome: Clinical Picture and Therapeutic Options<br>70. Resources for the Neuroscience of Alcohol</p>
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        Neuroscience of Alcohol