M. A. Hayat
Elsevier Science
e druk, 2017
9780128121467
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging
Volume 12
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2017
ISBN13: 9780128121467
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.
Specificaties
Inhoudsopgave
<p>I. MOLECULAR MECHANISMS<br>1. Overview of Autophagy <br>2. The Role of Autophagy in Ageing: Molecular Mechanisms<br>3. The Role of p62 in Aggregopathies<br>4. Role of Autophagy in the Transition from Monocyte to Differentiation<br>5. CDC48 AAA ATPASE Regulates Protein Dynamics and Turnover in Mitochondria<br>6. Autophagy in Plasma Cells <br>7. Loss of Pink1 or Parkin Function Results in a Progressive Loss of Mitochondrial Function<br>8. Role of the Transcription Factor IRF-1 in Regulating Autophagy in Lipopolysaccharide Stimulated Macrophages<br>9. mTOR: The Alpha and Omega of Autophagy Regulation<br>10. ER-phagy in Starvation, ER Stress, and Quality Control<br>11. Role of Autophagy Inhibition in Tumor Proliferative Arrest<br>12. Survival at the Brink: Chromatin Autophagy of Tumour Cells in Response to Genotoxic Challenge<br>13. Loss of Autophagy in Hypothalmic Neurons May be Involved in the Pathogenesis of Obesity<br>14. Defective Autophagy in Mesenteric Fat Tissue Maintains Inflammation in Crohn's Disease<br>15. Autophagy Regulates Inflammatory Responses in Antigen Presenting Cells: Underlying Mechanisms <br>16. Autophagy Accompanies Inflammasome Activation Moderating Inflammation by Eliminating Active Inflammasomes<br>17. Autophagy, Inflammation, and Breast Cancer Risk<br>18. AMBRA-Mediated regulation of V-MYC and its Relevance to Cancer <br>19. The Delicate Balance of Autophagy in Neurodegeneration<br>20. Silibinin Protects Uvb-Irradiated Skin by Balancing Apoptosis and Autophagy in Epidermis and Dermis<br>21. Role of Autophagy Activation in Alleviating Alcohol Neurotoxicity<br>22. Lipopolysaccharide-Enhanced Bactericidal Activity is Mediated by Induction of the Autophagosomal Process<br>23. Role of Autophagy in Liver Regeneration<br>24. A Dual Role of a Soluble N-Ethylmaleimide Sensitive Factor-Attachment Protein Alpha (-Snap) in the Regulation of Autophagy <br>25. TRAIL Induces Autophagic Protein Cleavage in Melanoma Cells</p>