Viral Proteases and Their Inhibitors

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2017
ISBN13: 9780128097120
Rubricering
Elsevier Science e druk, 2017 9780128097120
€ 127,00
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Samenvatting

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.

Specificaties

ISBN13:9780128097120
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>1. Fundamentals of Viruses and Their Proteases<br>Anjana Sharma and Satya P. Gupta<br>2. Design and Development of Some Viral Protease Inhibitors by QSAR and Molecular Modeling Studies<br>Noha Saleh Hanan Elhaes and Medhat Ibrahim<br>3. Advances in Studies on Adenovirus Proteases and Their Inhibitors<br>Satya P. Gupta Basheerulla Shaik and Y. S. Prabhakar<br>4. Alpha-virus Nonstructural Proteases and Their Inhibitors<br>Akalabya Bissoyi, Subrat Kumar<SUP> </SUP>Pattanayak Arindam Bit Ashish Patel, Abhishek <br>5. Structure and Function of Alphavirus Protease<br>Shailly Tomar and Megha Aggarwal<br>6. Flavivirus Protease: An Antiviral Target<br>Shailly Tomar, Rajat Mudgal and Benazir Fatma<br>7. Flavivirus NSB/NS3 Protease: Structure, Function, and Inhibition<br>Zhong Li Jing Zhang Hongmin Li<br>8. Design and Development of HCV NS5B Polymerase Inhibitors<br>Debasis Das<br>9. Studies on HIV-1 Protease and its Inhibitors<br>Sonal Dubey<br>10. Studies on Picornaviral Proteases and Their Inhibitors<br>Vaishali M. Patil<SUP> </SUP>and Satya P. Gupta<br>11. Structural Insight into the Viral 3C-like Protease inhibitors: Comparative SAR/QSAR Approaches<br>Nilanjan Adhikari Sandip Kumar Baidya Achintya Saha, Tarun Jha<br>12. Herpesvirus Proteases: Structure, Function, and Inhibition<br>Kriti Kashyap and Rita Kakkar<br>13. Design and Development of Inhibitors of Herpes Viral Proteases and Their SAR and QSAR<br>Dimitra Hadjipavlou-Litina and Satya P Gupta<br>14. Delicate Dance in Treating Hepatitis C Infections and Overcoming Resistance<br>Dolly A. Parasrampuria</p>
€ 127,00
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        Viral Proteases and Their Inhibitors