<p>1. On the Natural and Unnatural History of the Voltage-Gated Na+ Channel<br>Edward G. Moczydlowski<br>2. Biophysical Adaptations of Prokaryotic Voltage Gated Sodium Channels<br>Thuy N. Vien and Paul G. DeCaen<br>3. Venom Peptides from Cone Snails: Pharmacological Probes for Voltage-Gated Sodium Channels<br>Brad R. Green and Baldomero M. Olivera<br>4. Convergent Evolution of Tetrodotoxin-Resistant Sodium Channels in Predators and Prey<br>Gabriela Toledo, Charles Hanifin, Shana Geffeney and Edmund D. Brodie III<br>5. Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels<br>Boris S. Zhorov and Denis B. Tikhonov<br>6. Understanding Sodium Channel Function and Modulation Using Atomistic Simulations of Bacterial Channel Structures<br>Céline Boiteux and Toby W. Allen<br>7. Voltage-Gated Sodium Channels: Mechanistic Insights from Atomistic Molecular Dynamics Simulations<br>Victoria Oakes, Simone Furini and Carmen Domene<br>8. Simulation Studies of Ion Permeation and Selectivity in Voltage-Gated Sodium Channels<br>Christopher Ing and Régis Pomès<br>9. Voltage-Gated Sodium Channels: Evolutionary History and Distinctive Sequence Features<br>Marina A. Kasimova, Daniele Granata and Vincenzo Carnevale<br>10. Cardiac Na Channels: Structure to Function<br>Kevin R. DeMarco and Colleen E. Clancy<br>11. Developmental and Regulatory Functions of Na+ Channel Non-pore-forming Subunits<br>Jesse J. Winters and Lori L. Isom<br>12. Lipid Regulation of Sodium Channels<br>Nazzareno D’Avanzo<br>13. Mechanism of Inactivation in Voltage-Gated Na+ Channels<br>Vaibhavkumar S. Gawali and Hannes Todt<br>14. Current-Voltage Relationship for Late Na+ Current in Adult Rat Ventricular Myocytes<br>R. B. Clark and Wayne R. Giles<br>15. Physiology and Pathophysiology of Sodium Channel Inactivation<br>Mohammad-Reza Ghovanloo, Kelsey Aimar, Rouzbeh Ghadiry-Tavi, Alec Yu and Peter C. Ruben<br>16. Cardiac Sodium Channel Mutations: Why So Many Phenotypes?<br>Man Liu, Kai-Chien Yang and Samuel C. Dudley Jr.<br>17. Nav Channels in Damaged Membranes<br>Catherine E. Morris and Béla Joos<br>18. Unusual Voltage-Gated Sodium Currents as Targets for Pain<br>Cindy Barbosa and Theodore R. Cummins</p>