The Zebrafish: Disease Models and Chemical Screens

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2017
ISBN13: 9780128034736
Rubricering
Elsevier Science e druk, 2017 9780128034736
Onderdeel van serie Methods in Cell Biology
€ 188,50
Levertijd ongeveer 8 werkdagen

Specificaties

ISBN13:9780128034736
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Part I: Adipose Tissue1. In vivo imaging and quantification of regional adiposity in zebrafish</p> <p>Part II: Innate and Adaptive Immune Systems2. Innate immune cells and bacterial infection in zebrafish3. Best practices for germ-free derivation and gnotobiotic zebrafish husbandry4. Infectious disease models in zebrafish5. Live imaging the earliest host innate immune response to preneoplastic cells using a zebrafish inducible KalTA4-ERT2/UAS system6. Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells</p> <p>Part III: Blood and Lymph7. Hematopoietic stem cell development: Using the zebrafish to identify extrinsic and intrinsic mechanisms regulating hematopoiesis8. Studying disorders of vertebrate iron and heme metabolism using zebrafish9. The lymphatic vasculature revisited—new developments in the zebrafish</p> <p>Part IV: Visceral Organs10. Modeling intestinal disorders using zebrafish11. Analysis of pancreatic disease in zebrafish</p> <p>Part V: Musculoskeletal System12. Using the zebrafish to understand tendon development and repair13. Small teleost fish provide new insights into human skeletal diseases14. Muscular dystrophy modeling in zebrafish</p> <p>Part VI: Central and Sensory Nervous Systems15. Analysis of myelinated axon formation in zebrafish16. Zebrafish models of human eye and inner ear diseases</p> <p>Part VII: Cancer17. A zebrafish xenograft model for studying human cancer stem cells in distant metastasis and therapy response18. Zebrafish as a model for von Hippel Lindau and hypoxia-inducible factor signaling19. Discovering novel oncogenic pathways and new therapies using zebrafish models of sarcoma20. Zebrafish models of leukemia21. Investigating microglia-brain tumor cell interactions in vivo in the larval zebrafish brain</p> <p>Part VIII: Transplantation22. Transplantation in zebrafish</p> <p>Part IX: Chemical Screening23. Chemical screening in zebrafish for novel biological and therapeutic discovery</p>
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        The Zebrafish: Disease Models and Chemical Screens