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Genome Stability

From Virus to Human Application

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2016
ISBN13: 9780128033098
Rubricering
Elsevier Science e druk, 2016 9780128033098
€ 147,40
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Samenvatting

Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. Genome Stability teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments.

Genome Stability covers a wide range of topics, including the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes and mammals. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability as well as changes in genome stability in response to aging. Finally, Genome Stability covers how epigenetic factors contribute to genome stability and how the species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly-expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.

Specificaties

ISBN13:9780128033098
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. Genome stability – an evolutionary perspective<br>Igor Kovalchuk</p> <p>I. Genome Instability of Viruses</p> <p>2. Genetic Instability of RNA Viruses<br>John N. Barr and Rachel Fearns<br>3. Genome instability in DNA viruses<br>Rafael Sanjuán, Marianoel Pereira-Gómez, Jennifer Risso</p> <p>II. Genome instability in Bacteria and Archaea</p> <p>4. Genome instability in bacteria and archaea: Strategies for maintaining genome stability<br>Jan-Erik Messling and Ashley B. Williams</p> <p>5. Genome instability in bacteria: causes and consequences<br>Ashley B. Williams</p> <p>6. CRISPR - bacteria immune system<br>Andrey Golubov</p> <p>III. Genome Stability of Unicellular Eukaryotes</p> <p>7. Programmed DNA rearrangement in ciliates <br>Franziska Jönsson</p> <p>8. Homologous Recombination and Non-homologous End-joining repair in yeast<br>Rebecca E. Jones and Timothy C. Humphrey</p> <p>IV. Genome stability in multicellular eukaryotes</p> <p>9. Meiotic and Mitotic Recombination: First in Flies<br>Julie Korda Holsclaw, Talia Hatkevich and  Jeff Sekelsky</p> <p>10. Genome stability in Drosophila – mismatch repair and genome stability<br>Tomoe Negishi</p> <p>11. Genome stability in Caenorhabditis elegans<br>Matthias Rieckher, Amanda Franqueira C. Lopes and Björn Schumacher</p> <p>12. Genetic Engineering of Plants using Zn-fingers, TALENs and CRISPRs<br>Andriy Bilichak and Francois Eudes</p> <p>13. Plant Genome Stability – General Mechanisms<br>Andriy Bilichak</p> <p>V. Genome stability in mammals</p> <p>14. Cell cycle control and DNA damage signalling in mammals<br>Valenti Gomez and Alexander Hergovich</p> <p>15. The role of p53/p21/p16 in DNA damage signalling and DNA repair<br>Yavuz Kulaberoglu, Ramazan Gundogdu, and Alexander Hergovich</p> <p>16. Roles of RAD18 in DNA Replication and Post-Replication Repair (PRR)<br>Cyrus Vaziri, Satoshi Tateishi, Liz Mutter-Rottmayer and Yanzhe Gao</p> <p>17. Base Excision Repair and Nucleotide Excision Repair<br>Tadahide Izumi and Isabel Mellon</p> <p>18. DNA Mismatch Repair in Mammals<br>Mingzhang Yang and Peggy Hsieh</p> <p>19. Repair of double strand breaks by non-homologous end joining; its components and their function<br>Patryk Moskwa</p> <p>20. Double-Strand Break Repair: Homologous Recombination in Mammalian Cells<br>Camille Gelot, Tangui Le-Guen, Sandrine Ragu and Bernard S. Lopez</p> <p>21. Telomere maintenance and genome stability<br>Wilnelly Hernandez-Sanchez, Mengyuan Xu and Derek J. Taylor</p> <p>22. The relationship between checkpoint adaptation and mitotic catastrophe in genomic changes in cancer cells<br>Lucy H. Swift and Roy M. Golsteyn</p> <p>23. Chromatin, nuclear organization and genome stability in mammals <br>Lora Boteva, Nick Gilbert</p> <p>24. Role of DNA methylation in genome stability<br>Dan Zhou and Keith D. Robertson</p> <p>25. Non-coding RNAs in genome integrity<br>Igor Kovalchuk</p> <p><br>VI. Human diseases associated with genome instability<br>26. Human diseases associated with genome instability<br>Bruno César Feltes, Joice de Faria Poloni, Kendi Nishino Miyamoto and Diego Bonatto</p> <p>27. Cancer and genomic instability<br>Wei Wei, Yabin Cheng and Bo Wang</p> <p>28. Chromatin Modifications in DNA Repair and Cancer<br>Margaret Renaud-Young, Karl Riabowol and Jennifer Cobb</p> <p>29. Genomic Instability and Aging – Causes and Consequences<br>Corinne Sidler</p> <p>30. Nucleolar contributions to DNA damage response and genomic (in)stability in the nervous system<br>Michal Hetman</p> <p>VII. Effect of environment on genome stability</p> <p>31. Diet and nutrition<br>Lynnette R. Ferguson</p> <p>32. Chemical mutagenesis</p> <p>33. Environmental sources of ionizing radiation and their health consequences<br>Aaron A. Goodarzi, Alexander Anikin, Dustin D. Pearson</p> <p>Section VIII. Bystander and transgenerational effects – epigenetic perspective</p> <p>34. Epigenetics of transgenerational genome instability in mammals</p> <p>35. Genomic Instability and the Spectrum of Response to Low Radiation Doses<br>Carmel Mothersill and Colin Seymour</p> <p>36. Transgenerational genome instability in plants<br>Igor Kovalchuk</p> <p>37. Methods for the detection of DNA damage<br>Denis V. Firsanov, Ljudmila V. Solovjeva, Vyacheslav M. Mikhailov, Maria P. Svetlova</p> <p>38. Conserved and divergent features of DNA repair. Future perspectives in genome instability research<br>Igor Kovalchuk<br></p>
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