Douglas W Houston
Elsevier Science
e druk, 2017
9780128024386
Cell Polarity in Development and Disease
Specificaties
Paperback, blz.
|
Engels
Elsevier Science |
e druk, 2017
ISBN13: 9780128024386
Rubricering
Onderdeel van serie
Perspectives in Translational Cell Biology
Levertijd ongeveer 8 werkdagen
Samenvatting
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research.
Specificaties
Inhoudsopgave
1. Overview of cell polarity: insights from model organisms and cellular systems<br>2. Cell polarity in the egg and early embyro- mammal<br>3. Pluripotency and cell polarity<br>4. The role of cell polarity in adult stem cell maintenance<br>5. Integration of cell polarity and growth factor signaling<br>6. Cell polarity and the onset and progression of cancer<br>7. Cell division and cell polarity<br>8. Polarized membrane/vesicle trafficking and disease<br>9. Polarized microtubule transport and disease<br>10. Regulation of cell polarity in cell/neuronal migration<br>11. Apical and planar cell polarity in ciliated epithelia<br>12. Renal epithelial cell polarity and disease<br>13. Hepatic cell polarity and disease<br>14. Epidermal cell polarity and disease<br>15. Cell polarity and sensory cell defects<br>