Nicholas M Boulis,
Deirdre O’Connor,
Anthony Donsante
Elsevier Science
e druk, 2017
9780128022573
Molecular and Cellular Therapies for Motor Neuron Diseases
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2017
ISBN13: 9780128022573
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.
Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
Specificaties
Inhoudsopgave
<p>1. Molecular and Extracellular Cues in Motor Neuron Specification and Differentiation<br>2. Natural History of Amyotrophic Lateral Sclerosis<br>3. Genetics of Amyotrophic Lateral Sclerosis<br>4. Molecular Mechanisms of Amyotrophic Lateral Sclerosis<br>5. An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy<br>6. Genetics of Spinal Muscular Atrophy<br>7. Introduction to Gene and Stem-Cell Therapy<br>8. Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes<br>9. Stem Cell Therapy for Amyotrophic Lateral Sclerosis<br>10. Gene Therapy for Spinal Muscular Atrophy<br>11. Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls<br>12. Clinical Trials to Date</p>