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Viral Pathogenesis

From Basics to Systems Biology

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2016
ISBN13: 9780128009642
Rubricering
Elsevier Science e druk, 2016 9780128009642
€ 87,34
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Samenvatting

Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized.

The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome.

In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology.

Specificaties

ISBN13:9780128009642
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>Viral Pathogenesis: From Basics to Systems Biology</p> <p>1. The Human Toll of Viral Diseases: Past plagues and pending pandemics</p> <p>Neal Nathanson</p> <p>2. Historical Roots: The family tree of viral pathogenesis</p> <p>William C. Summers</p> <p>3. Basic Concepts: A step-by-step guide to viral infection</p> <p>Robert Doms</p> <p>4. Innate Immunity: Recognizing and responding to foreign invaders—no training needed</p> <p>Christine A. Biron</p> <p>5. Adaptive Immunity: Neutralizing, eliminating, and remembering for the next time</p> <p>E. John Wherry, David Masopust</p> <p>6. Aberrant Immunity: The consequences of overreacting or underperforming</p> <p>E. John Wherry, David Masopust</p> <p>7. Patterns of infection: Unwanted guests—quick visits and extended stays </p> <p>Neal Nathanson and Francisco González-Scarano</p> <p>8. Viral Oncogenesis: Infections That Can Lead to Cancer</p> <p>Nicholas A. Wallace and Denise A. Galloway</p> <p>9. HIV and AIDS: Science wrestles with 10,000 nucleotides—points but no pin</p> <p>Guido Silvestri and Emily Cartwright</p> <p>10. Animal Models: No model is perfect, but many are useful</p> <p>Victoria K. Baxter and Diane E. Griffin</p> <p>11. Systems Virology: Why Everybody Wants To Measure Everything</p> <p>Marcus J. Korth and G. Lynn Law</p> <p>12. The Virus-Host Interactome: Knowing the players to understand the game</p> <p>Monika Schneider, Jeffery R. Johnson, Nevan J. Krogan, and Sumit K. Chanda</p> <p>13. Host Genetics: It’s not just the Virus, Stupid</p> <p>Martin T. Ferris, Mark T. Heise, and Ralph S. Baric</p> <p>14. Host metabolomics: Yet more ways your health is influenced by fat </p> <p>Priscilla Yang</p> <p>15. Mathematical Modeling: Solving equations to measure viral diseases – math rules</p> <p>Alan S Perelson</p> <p>16. Emerging viral diseases: Why we need to worry about bats, camels, and airplanes</p> <p>James W. Le Duc and Neal Nathanson</p> <p>17. Viral evolution: It’s all about mutations</p> <p>Adi Stern and Raul Andino</p> <p>18. Viral Epidemiology: Tracking viruses with smartphones and social media</p> <p>Kaitlin Rainwater-Lovett, Isabel Rodriguez-Barraquer and William J. Moss</p> <p>19. Viral Vaccines: Fighting viruses with viruses</p> <p>Juliet Morrison and Stanley Plotkin</p> <p>20. Antiviral Therapy</p> <p>Douglas D. Richman and Neal Nathanson</p> <p>21. Breakthrough: Nobel prize discoveries in viral pathogenesis</p> <p>Neal Nathanson</p> <p>22. What lies ahead? Scientists look into their crystal balls</p>
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