<p>Viral Pathogenesis: From Basics to Systems Biology</p> <p>1. The Human Toll of Viral Diseases: Past plagues and pending pandemics</p> <p>Neal Nathanson</p> <p>2. Historical Roots: The family tree of viral pathogenesis</p> <p>William C. Summers</p> <p>3. Basic Concepts: A step-by-step guide to viral infection</p> <p>Robert Doms</p> <p>4. Innate Immunity: Recognizing and responding to foreign invaders—no training needed</p> <p>Christine A. Biron</p> <p>5. Adaptive Immunity: Neutralizing, eliminating, and remembering for the next time</p> <p>E. John Wherry, David Masopust</p> <p>6. Aberrant Immunity: The consequences of overreacting or underperforming</p> <p>E. John Wherry, David Masopust</p> <p>7. Patterns of infection: Unwanted guests—quick visits and extended stays </p> <p>Neal Nathanson and Francisco González-Scarano</p> <p>8. Viral Oncogenesis: Infections That Can Lead to Cancer</p> <p>Nicholas A. Wallace and Denise A. Galloway</p> <p>9. HIV and AIDS: Science wrestles with 10,000 nucleotides—points but no pin</p> <p>Guido Silvestri and Emily Cartwright</p> <p>10. Animal Models: No model is perfect, but many are useful</p> <p>Victoria K. Baxter and Diane E. Griffin</p> <p>11. Systems Virology: Why Everybody Wants To Measure Everything</p> <p>Marcus J. Korth and G. Lynn Law</p> <p>12. The Virus-Host Interactome: Knowing the players to understand the game</p> <p>Monika Schneider, Jeffery R. Johnson, Nevan J. Krogan, and Sumit K. Chanda</p> <p>13. Host Genetics: It’s not just the Virus, Stupid</p> <p>Martin T. Ferris, Mark T. Heise, and Ralph S. Baric</p> <p>14. Host metabolomics: Yet more ways your health is influenced by fat </p> <p>Priscilla Yang</p> <p>15. Mathematical Modeling: Solving equations to measure viral diseases – math rules</p> <p>Alan S Perelson</p> <p>16. Emerging viral diseases: Why we need to worry about bats, camels, and airplanes</p> <p>James W. Le Duc and Neal Nathanson</p> <p>17. Viral evolution: It’s all about mutations</p> <p>Adi Stern and Raul Andino</p> <p>18. Viral Epidemiology: Tracking viruses with smartphones and social media</p> <p>Kaitlin Rainwater-Lovett, Isabel Rodriguez-Barraquer and William J. Moss</p> <p>19. Viral Vaccines: Fighting viruses with viruses</p> <p>Juliet Morrison and Stanley Plotkin</p> <p>20. Antiviral Therapy</p> <p>Douglas D. Richman and Neal Nathanson</p> <p>21. Breakthrough: Nobel prize discoveries in viral pathogenesis</p> <p>Neal Nathanson</p> <p>22. What lies ahead? Scientists look into their crystal balls</p>