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Personalized Epigenetics

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2015
ISBN13: 9780124201354
Rubricering
Elsevier Science e druk, 2015 9780124201354
€ 104,14
Levertijd ongeveer 8 werkdagen

Samenvatting

Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy.

The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics.

Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.

Specificaties

ISBN13:9780124201354
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Section I: Overview</p> <p>1. Epigenetics of Personalized Medicine</p> <p>Section II: Epigenetic Variations Among Individuals</p> <p>2. Inter-individual Variability of DNA Methylation</p> <p>3. Differences in Histone Modifications Between Individuals</p> <p>4. Individual Noncoding RNA Variations: Their Role in Shaping and Maintaining the Epigenetic Landscape</p> <p>5. Personalized Epigenetics: Analysis and Interpretation of DNA Methylation Variation</p> <p>Section III: Bioinformatics of Personalized Epigenetics</p> <p>6. Computational Methods in Epigenetics</p> <p>Section IV: Diagnostic and Prognostic Epigenetic Approaches to Personalized Medicine</p> <p>7. Epigenetic Biomarkers in Personalized Medicine</p> <p>8. Epigenetic ‘Fingerprint’</p> <p>9. Epigenetics of Personalized Toxicology</p> <p>Section V: Environmental Personalized Epigenetics</p> <p>10. Environmental Contaminants and their Impacts on the Epigenome</p> <p>11. Nutriepigenomics: Personalized Nutrition Meets Epigenetics</p> <p>Section VI. Pharmacology and Drug Development of Personalized Epigenetics</p> <p>12. Personalized Pharmacoepigenomics</p> <p>13. Personalized Medicine and Epigenetic Drug Development</p> <p>Section VII: Personalized Epigenetics of Disorders and Disease Management</p> <p>14. Epigenetics and Personalized Pain Management</p> <p>15. Understanding Inter-individual Epigenetic Variations in Obesity and its Management </p> <p>16. Epigenetic Modification of miRNAs in Cancer</p> <p>17. Managing Autoimmune Disorders Through Personalized Epigenetic Approaches</p> <p>18. Cardiovascular Diseases and Personalized Epigenetics</p> <p>Section VIII: Challenges and Future Directions</p> <p>19. Future Challenges and Prospects for Personalized Epigenetics</p>
€ 104,14
Levertijd ongeveer 8 werkdagen

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        Personalized Epigenetics