Antonio Noronha,
Changhai Cui,
Robert Adron Harris,
John C. Crabbe
e.a.
Elsevier Science
e druk, 2014
9780124059412
Neurobiology of Alcohol Dependence
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2014
ISBN13: 9780124059412
Rubricering
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence.
Specificaties
Inhoudsopgave
<p>Section I: Neurocircuitry of Alcohol Dependence <br>1. Frameworks of alcohol addiction: Alcohol addiction as a reward deficit and stress surfeit disorder<br>2. Basal ganglia networks and mechanisms of voluntary actions: implications for alcohol addiction and dependence<br>3. Prefrontal limbic striatal circuits and alcohol addiction in humans<br>4. Molecular adaptations in mesolimbic circuitry and pathological ethanol intake<br>5. The bed nucleus of the stria terminalis: A critical site of ethanol-induced alterations in neurotransmission<br>6. Stress and alcohol drinking behavior<br>7. Alcohol and developing neuronal circuits<br>8. Human imaging studies of brain circuitry disrupted by alcoholism<br><br>Section II: Neurosignaling and Neuroplasticity of Alcohol Dependence <br>9. From signaling pathways to behavior: The light and dark sides of alcohol<br>10. Glutamate signaling in alcohol abuse and dependence<br>11. Central amygdala neuroplasticity in alcohol dependence <br>12. Neural plasticity in the ventral tegmental area and alcohol dependence<br>13. Extrasynaptic GABA receptors and alcohol <br>14. Cannabinoids and the neural actions of alcohol<br>15. Impact of alcohol abuse and dependence on the structure and function of the prefrontal cortex<br>16. Molecular mechanisms underlying the development of functional and behavioral tolerance to alcohol<br><br>Section III: Gene and Behavior<br>17. Alcohol and the brain: An epigenetic viewpoint<br>18. The genetic complexity of alcohol drinking in rodents<br>19. Alcohol dependence, withdrawal, and relapse<br>20. Insights from non human primates on risks for drinking to dependence<br>21. The potential role of glucocorticoids and the HPA axis in alcohol dependence<br>22. Anxiety and alcohol use disorders: A perspective from molecular and epigenetic studies<br>23. The genetics of alcohol responses of invertebrate model systems<br>24. MicroRNAs in alcohol abuse and toxicity<br>25. Gene and behavior<br>26. Complex genetics of alcoholism </p>