Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2013
ISBN13: 9780123945877
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Elsevier Science e druk, 2013 9780123945877
€ 162,25
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Samenvatting

In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology.

Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research.

Specificaties

ISBN13:9780123945877
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<ol> <li>Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning Receptors</li> <p>Michael T. Klein, Paige N. Vinson and Colleen M. Niswender</p> <p> <li>Pharmacology of Metabotropic Glutamate Receptor Allosteric Modulators: Structural Basis and Therapeutic Potential for CNS Disorders</li> <p>Karen J. Gregory, Meredith J. Noetzel and Colleen M. Niswender</p> <p> <li>Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor Drug Discovery</li> <p>Magalie Rochville, Julio Martin, Jeffrey Clifford Jerman & Evi Kostenis</p> <p> <li>G Protein-Coupled Receptors in Cancer : Biochemical Interactions and Drug Design</li> <p>Yves Audigier, François-Xavier Picault, Carline Chaves-Almagro and Bernard Masri</p> <p> <li>GPCRs in Stem Cell Function</li> <p>Van A. Doze and Dianne M. Perez</p> <p> <li>Application of Receptor Theory to Allosteric Modulation of Receptors</li> <p>David A. Hall</p> <p> <li>What Ligand-Gated Ion Channels Can Tell Us about the Allosteric Regulation of G protein-Coupled Receptors</li> <p>Frederick J. Ehlert</p> <p> <li>Modelling Cooperativity Effects in Dimeric G Protein-Coupled Receptors</li> <p>Jesús Giraldo</p> <p> <li>Chemokine Receptor Oligomerization and Allostery</li> <p>Bryan Stephens and Tracy M. Handel</p> <p> <li>Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators<br><br>Peishen Zhao, Wendy Cladman, Hubert HM Van Tol and Peter Chidiac</li></ol>
€ 162,25
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        Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors