Louis M. Luttrell
Elsevier Science
e druk, 2013
9780123944405
The Molecular Biology of Arrestins
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2013
ISBN13: 9780123944405
Rubricering
Onderdeel van serie
Progress in Molecular Biology and Translational Science
Levertijd ongeveer 8 werkdagen
Samenvatting
This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with reviews written by experts in the field.
Specificaties
Inhoudsopgave
<p>Part I: Perspective - The Duality of Arrestin Function</p> <p>1. Arrestins Come of Age: A Personal Historical Perspective</p> <p>Part II: The Molecular Biology of Arrestins</p> <ol> </ol> <p>2. True Arrestins and Arrestin-Fold Proteins: A Structure-Based Appraisal</p> <ol> </ol> <p>3. Structural Determinants of Arrestin Functions</p> <ol> </ol> <p>4. Arrestins: Role in the Desensitization, Sequestration and Vesicular Trafficking of G Protein-Coupled Receptors</p> <ol> </ol> <p>5. Arrestins as Regulators of Kinases and Phosphatases</p> <ol> </ol> <p>6. ß-Arrestins: Modulators of Small GTPase Activation and Function</p> <ol> </ol> <p>7. Arrestins and Protein Ubiquitination</p> <ol> </ol> <p>8. Arrestins in Actin Reorganization and Cell Migration</p> <p>Part III: The Physiological Roles of Arrestins</p> <ol> </ol> <p>9. The Role of Arrestins in Development</p> <ol> </ol> <p>10. The Role of Arrestins in Visual and Disease Processes of the Eye</p> <ol> </ol> <p>11. b-Arrestins in the Central Nervous System</p> <ol> </ol> <p>12. Arrestins in the Cardiovascular System</p> <ol> </ol> <p>13. Arrestins in Bone</p> <ol> </ol> <p>14. b-Arrestins in the Immune System</p> <ol> </ol> <p>15. The Role of b-Arrestins in Cancer</p> <ol> </ol> <p>16. Arrestins in Metabolic Regulation</p> <p>Part IV: The Future - The Potential for Arrestin-based Therapeutics</p> <ol> </ol> <p>17. Systems Analysis of Arrestin Pathway Functions</p> <ol> </ol> <p>18. Arrestin Pathways as Drug Targets</p> <ol> </ol>