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Mitochondrial Function, Part B

Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2009
ISBN13: 9780123746221
Rubricering
Elsevier Science e druk, 2009 9780123746221
Onderdeel van serie Methods in Enzymology
€ 213,50
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Samenvatting

In this second of two new volumes covering mitochondria, methods developed to assess the number and function of nuclear-encoded proteins in the mitochondrion are presented. Chapters focus on the regulation of mitochondrial function and mitochondrial diseases, with a section emphasizing the mitochondrial defects associated with type 2 diabetes.

The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. With more than 450 volumes published, each volume presents material that is relevant in today's labs, truly an essential publication for researchers in all fields of life sciences.

Specificaties

ISBN13:9780123746221
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Defining the Mitochondrial Proteome<br>1. Method to define the mammalian mitochondrial proteome; V. Mootha<br>2. Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry; X.Fang and C. S. Lee <br>3. Method to analyze tissue heterogeneity of the mammalian mitochondrial proteome; R. S. Balaban <br>4. Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data; D. Gaston, A. Tsausis and A. Roger <br>5. MitoP2: the mitochondrial proteome database; H. Prokisch <br><br>Post-Translational Modifications of Mitochondrial Proteins<br>6. Reversible protein acetylation in mitochondria; E. Verdin<br>7.Post-translational modifications of rat liver mitochondria outer membrane proteins' C. L. Hoppel<br>8.Characterization of a novel ser/thr protein phosphatase in mitochondria; Y. Wang <br>9. R. Rizzuto <br>10.Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins; G. Pocsfalvi <br>11. Isolation of Regulatory-competent, Phosphorylated Cytochrome c and Cytochrome c Oxidase; M. Hüttemann <br>12. Identification of tyrosine phosphorylated proteins by Src kinases in rat brain; M. Salvi <br>13. Detection of a mitochondrial kinase complex that mediates an ERK-dependent phosphorylation of mitochondrial protein in steroid biosynthesis; E. J. Podestá <br>14. Dual specific phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane; J. Rardin & J. E. Dixon <br>15.M. A. Kostiuk and B. O. Keller: “Isolation and identification of palmitoylated proteins in mitochondria using a chemical biology approach; L. G. Berthiaume <br><br>Mitochondrial Dynamics <br>16.Mitochondrial fusion and movement using photoactivatable GFP; O. Shirihai <br>17. Regulation of mitochondrial fission and fusion by kinase and phosphatase activities. no title yet; S. Strack <br>18. Mitochondrial movement and synaptic function in Drosophila; T. L. Schwarz <br>19. The use of yeast and a novel biosensor to study mitochondrial ion transport, swelling, and mitophagy; R. J. Scheweyen <br>20.Complete Exchange of mtDNA’s between Mouse Cells for Testing the Effects of mtDNA on Tumor Phenotypes; J. Hayashi<br><br>Mitochondrial Function in Pancreatic Beta Cells<br>21. Coupling efficiency INS-1E cells; M. D. Brand and C. Affourtit <br>22. Methods in the study of substrate-specific differences on mitochondrial function mediating insulin secretion from pancreatic beta cells; B. E. Corkey <br>23. Knocking down of UCP 2 in animal models of obesity; L. A.Velloso<br>24.Roles of the cytosolic and mitochondrial forms of the malic enzyme on insulin secretion; G. W. Cline<br>25. Altered regulation of the PINK1 locus as a link between type 2 diabetes and neurodegeneration; J. A. Timmons <br>26. Insulin secretion from pancreatic beta cells is affected deletion of the nicotinamide nucleotide transhydrogenase; R. D. Cox<br>27. Determination of oxidative capacity and mitochondrial function in insulin resistance and type 2 diabetes; G. Shulman et al <br>28.Mitochondrial ATP production rate; K. S. Nair </p>
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