David A. Cheresh
Elsevier Science
e druk, 2008
9780123743152
Angiogenesis: In Vitro Systems
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2008
ISBN13: 9780123743152
Rubricering
Onderdeel van serie
Methods in Enzymology
Levertijd ongeveer 8 werkdagen
Samenvatting
Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over antiogenesis. Diseases that are angiogensis-dependent result when blood vessels either grow excessively or insufficiently.
Specificaties
ISBN13:9780123743152
Taal:Engels
Bindwijze:Gebonden
Uitgever:Elsevier Science
Serie:Methods in Enzymology
Inhoudsopgave
Studying cell signaling pathways; Flow mediated signaling; Endothelial cell adhesion and migration on the ECM; EC sprouting assays; Lumen formation assays; Isolation and propagation of EC's or SMC's; Cell-based assays to screen anti-angiogenic agents (chemical approach; ES cell models of vascular network formation; Co-culture studies with EC plus other cell types; Aortic ring sprouting (multiple cell types present); Effects of hypoxia or hyperoxia; Vascular Proteomics; In vitro vascular barrier function; EC leukocyte interactions; ECM signaling to the vasculature; Vascular Integrin signaling; Mechanical Signaling in blood vessels; Vascular and neuronal patterning; Vascular growth factors and their signals; VEGF receptor signal transduction; Development and testing of monoclonal antibodies directed to angiogenic targets.<br> <br>