Fuyuhiko Tamanoi,
David S. Sigman
Elsevier Science
e druk, 2000
9780121227227
Protein Lipidation
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
e druk, 2000
ISBN13: 9780121227227
Rubricering
Onderdeel van serie
The Enzymes
Levertijd ongeveer 8 werkdagen
Samenvatting
This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented.
Specificaties
Inhoudsopgave
Mechanism of Catalysis by Protein Farnesyltransferase<br>Structure of Protein Farnesyltransferase<br>Mutational Analyses of Protein Farnesyltransferase<br>Farnesyltransferase Inhibitors<br>Protein Geranylgeranyltransferase Type I<br>Biochemistry of Rab Geranylgeranyltransferase<br>Postisoprenylation Protein Processing: CXXX (CaaX) Endoproteases and Isoprenylcysteine Carboxyl Methyltransferase<br>Reversible Modification of Proteins with Thioester-Linked Fatty Acids<br>Biology and Enzymology of Protein N-Myristoylation<br>